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Merck
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主要文件

RAB0558

Sigma-Aldrich

小鼠Esm1 /内皮细胞特异性分子1 ELISA试剂盒

for serum, plasma and cell culture supernatants

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

mouse

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable

輸入

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.1 ng/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

mouse ... Esm1(71690)

一般說明

This ELISA antibody pair detects mouse Endothelial Cell-specific Molecule 1. Endothelial cell-specific molecule 1 (ESM1) is a secreted dermatan sulfate proteoglycan. This cysteine-rich protein is expressed in kidney glomeruli, specifically in renal epithelia and endothelial cells. Proangiogenic factors and cytokines modulate its activity.

應用

请参考Protocol了解详情。

生化/生理作用

Endothelial cell-specific molecule 1 (ESM1) may have a role in inflammation and angiogenesis. It has been linked to tumor growth. ESM1 stimulates vascular sprouting, growth, differentiation, migration and adhesion of cells.

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy.
Zheng X
PLoS ONE (2017)
Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1).
Cong R
Biochemical and Biophysical Research Communications (2006)
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma.
Chen C
Oncotarget (2016)
The non glycanated endocan polypeptide slows tumor growth by inducing stromal inflammatory reaction.
Yassine H
Oncotarget (2015)
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
Rocha SF
Circulation Research (2014)

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