推荐产品
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
capture ELISA: suitable
輸入
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.549-400 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... PDGFB(5155)
一般說明
The Human PDGF-BB ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PDGF-BB in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human PDGF-BB
應用
For research use only. Not for use in diagnostic procedures.
Human PDGF-BB ELISA Kit has been used to measure PDGF-BB (platelet-derived growth factor BB) concentration in human coronary artery smooth muscle cells (HCASMCs).
Human PDGF-BB ELISA Kit has been used to measure PDGF-BB (platelet-derived growth factor BB) concentration in human coronary artery smooth muscle cells (HCASMCs).
生化／生理作用
PDGF-BB (platelet-derived growth factor BB) stimulates lymphatic metastasis and intratumoral lymphangiogenesis. PDGF-BB might be implicated in regulation of angiogenesis and endothelial proliferation. PDGF-BB expressed in placental endothelial cell activates signal transducer and activator of transcription 3 (STAT3) pathway and recruits human placental multipotent mesenchymal stromal cells (hPMSCs) for placental vascularization. Heterozygous mutation in PDGF-B is associated with primary familial brain calcification.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis.
Cao R
Cancer Cell, 6(4), 333-345 (2004)
Role of Myoendothelial Gap Junctions in the Regulation of Human Coronary Artery Smooth Muscle Cell Differentiation by Laminar Shear Stress.
Zhang Z
Cellular Physiology and Biochemistry, 39(2), 423-437 (2016)
Callie Frey et al.
Platelets, 31(7), 952-959 (2020-01-15)
Patients with heart failure (HF) and left ventricular assist devices (LVAD) have dysregulated thrombo-inflammatory responses, mediated in part by platelets. While studies of platelet activation have been undertaken in HF, changes in the platelet transcriptome in HF patients following mechanical
PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.
Battegay EJ
The Journal of Cell Biology, 125(4), 917-928 (1994)
Shilpa Tiwari-Heckler et al.
Cell reports, 37(4), 109897-109897 (2021-10-28)
Elevated circulating activity of adenosine deaminase 2 (ADA2) is associated with liver fibrosis in nonalcoholic fatty liver disease (NAFLD). In the liver of NAFLD patients, ADA2-positive portal macrophages are significantly associated with the degree of liver fibrosis. These liver macrophages
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