推荐产品
生物源
synthetic (organic)
化驗
≥98% (HPLC)
形狀
powder
顏色
white
溶解度
DMSO: ~18 mg/mL
起源
Sanofi Aventis
儲存溫度
2-8°C
SMILES 字串
O=C(N1[C@](CCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@H](C)N[C@H](C(OCC)=O)CCC3=CC=CC=C3
InChI
1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChI 密鑰
HDACQVRGBOVJII-JBDAPHQKSA-N
基因資訊
human ... ACE(1636)
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生化／生理作用
Angiotensin converting enzyme (ACE) inhibitor.
特點和優勢
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Danger
危險聲明
危險分類
Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Daniela Dunkler et al.
JAMA internal medicine, 173(18), 1682-1692 (2013-08-14)
Type 2 diabetes mellitus and associated chronic kidney disease (CKD) have become major public health problems. Little is known about the influence of diet on the incidence or progression of CKD among individuals with type 2 diabetes. To examine the
Guillaume Pare et al.
Pharmacogenetics and genomics, 23(9), 470-478 (2013-07-11)
The objective of this study was to identify genetic variants associated with angiotensin-converting enzyme (ACE) inhibitor-associated angioedema. We carried out a genome-wide association study in 175 individuals with ACE inhibitor-associated angioedema and 489 ACE inhibitor-exposed controls from Nashville (Tennessee) and
Joshua I Barzilay et al.
Clinical journal of the American Society of Nephrology : CJASN, 8(2), 233-240 (2012-11-28)
The microvascular circulation plays an important role in bone health. This study examines whether albuminuria, a marker of renal microvascular disease, is associated with incident hip and pelvic fractures. This study reanalyzed data from the Ongoing Telmisartan Alone and in
G Castoldi et al.
American journal of nephrology, 37(1), 65-73 (2013-01-19)
Diabetic nephropathy is the main cause of end-stage renal disease. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), a physiological tetrapeptide hydrolyzed by the angiotensin-converting enzyme (ACE), has antifibrotic effects in the cardiovascular system and in the kidney in experimental models of hypertension, heart failure and
Carla Zoja et al.
American journal of physiology. Renal physiology, 304(6), F808-F819 (2012-11-09)
Bardoxolone methyl is an antioxidant inflammation modulator acting through induction of Keap1-Nrf2 pathway. Results from a recent phase IIb clinical trial reported that bardoxolone methyl was associated with improvement in the estimated glomerular filtration rate in patients with advanced chronic
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