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Merck

P7568

Sigma-Aldrich

β-乙酰基-γ-O-烷基-L-α-磷脂酰胆碱 来源于牛心脏卵磷脂

≥99%, lyophilized powder

别名:

1-O-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱, 2-乙酰基-1-烷基-sn-甘油-3-磷酸胆碱, AcGEPC, PAF, 血小板活化因子

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About This Item

CAS号:
Beilstein:
4220745
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥99%

形狀

lyophilized powder

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1

InChI 密鑰

HVAUUPRFYPCOCA-AREMUKBSSA-N

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生化/生理作用

淋巴细胞、血小板和内皮细胞产生的磷脂,可以诱导血小板聚集,与炎症、过敏以及创伤愈合有关。

包裝

在氩气下包装。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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F Bussolino et al.
Cell calcium, 5(5), 463-473 (1984-10-01)
Platelet-activating factor (1-0-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine, PAF) is a potent inducer of shape-change, aggregation and secretion in platelets. PAF causes a rapid increase in intracellular calcium, but has no calcium gating effect in intact lipid bilayers. Human red cells (RBC) did not metabolize
Julie R Jin et al.
Frontiers in immunology, 11, 585070-585070 (2020-11-17)
Mast cells are the major effector cells in immunoglobulin E (IgE)-mediated allergy. The high affinity IgE receptor FcεRI, as well as G protein-coupled receptors (GPCRs) on the mast cell surface signals to phosphoinositide 3-kinase γ (PI3Kγ) to initiate degranulation, cytokine
Stephanie Saul et al.
Journal of leukocyte biology, 106(5), 1101-1115 (2019-06-20)
Neutrophils play a central role in immunity and inflammation via their intrinsic ability to migrate into inflamed tissue, to phagocytose pathogens, and to kill bacterial and fungi by releasing large quantities of superoxide anions and lytic enzymes. The molecular pathways

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