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Merck

P6972

Sigma-Aldrich

Monoclonal Anti-Interferon-γ−R-Phycoerythrin antibody produced in mouse

clone 25723, purified immunoglobulin, saline solution

别名:

Monoclonal Anti-Interferon-γ

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About This Item

分類程式碼代碼:
51111800
NACRES:
NA.41

生物源

mouse

品質等級

共軛

phycoerythrin (R-PE) conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

25723, monoclonal

形狀

saline solution

物種活性

human

技術

flow cytometry: suitable

同型

IgG2b

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

human ... IFNG(3458)

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一般說明

Human Interferon-γ (IFN-γ) is a Type I cytokine produced by the lymphocytes activated in response to specific antigens or mitogens. It has a pivotal role in activating primed macrophages for nonspecific tumoricidal activity as well as can stimulate monocytes for enhanced cytotoxicity against tumor cells. It also has several biological functions like inhibition of cell or tumor growth, promotion of B cell differentiation into plasma cells and antiviral activity. Further, it can enhance the cytotoxicity of natural killer cells and T-cells. Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody reacts specifically with human IFN-γ.

特異性

The conjugates will identify and quantitate cells containing intracellular forms of human IFN-γ by flow cytometry.

免疫原

recombinant human IFN-γ

應用

Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody can be used in flow cytometry for detecting intracytoplasmic cytokines and enumerating cytokine-producing cells in a mixed population.

外觀

Solution in saline containing up to 0.5% bovine serum albumin and 0.1% sodium azide as a preservative.

準備報告

Purified antibody is conjugated to R-phycoerythrin (PE).

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Jamie R Schoenborn et al.
Advances in immunology, 96, 41-101 (2007-11-06)
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produced predominantly by natural killer (NK) and natural killer

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