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Merck

P6462

Sigma-Aldrich

Protein Tyrosine Phosphatase Substrate Monophosphate

≥97% (HPLC)

别名:

[pTyr1146]-Insulin Receptor fragment 1142-1153, PTPase Substrate Phosphate

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About This Item

经验公式(希尔记法):
C72H108N19O27P
分子量:
1702.71
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.84

化驗

≥97% (HPLC)

形狀

powder

儲存溫度

−20°C

Amino Acid Sequence

Thr-Arg-Asp-Ile-Tyr[PO3H2]-Glu-Thr-Asp-Tyr-Tyr-Arg-Lys

其他說明

Lyophilized from 0.1% TFA in H2O

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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L Stadtmauer et al.
The Journal of biological chemistry, 261(21), 10000-10005 (1986-07-25)
Three peptides were synthesized corresponding to potential autophosphorylation sites of the beta subunit of the human insulin receptor. These were peptide 1150 corresponding to amino acids 1142-1153 of the pro-receptor, peptide 960 corresponding to amino acids 952-961 of the proreceptor
M J King et al.
FEBS letters, 237(1-2), 137-140 (1988-09-12)
Synthetic peptide 1142-1153 of the insulin receptor was phosphorylated on tyrosine by the insulin receptor and found to be a potent substrate for dephosphorylation by rat liver particulate and soluble phosphotyrosyl protein phosphatases. Apparent Km values were approximately 5 microM.
T O'Hare et al.
The Journal of biological chemistry, 264(1), 602-610 (1989-01-05)
We are interested in developing methods to rigorously characterize the intrinsic enzymatic activity of the insulin receptor. We have previously shown that the intact, kinase active form of the receptor can be separated from inactive forms isolated from human placenta.
Bannwarth, W., and Kitas, E.A.
Helvetica Chimica Acta, 75, 707-707 (1992)

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