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Merck

P2871

Sigma-Aldrich

Anti-Cytokeratin pan antibody, Mouse monoclonal

clone C-11, purified from hybridoma cell culture

别名:

Anti-CK-4, Anti-CK4, Anti-CYK4, Anti-K4, Anti-WSN1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified from hybridoma cell culture

抗體產品種類

primary antibodies

無性繁殖

C-11, monoclonal

形狀

buffered aqueous solution

技術

immunocytochemistry: 15-30 μg/mL using methanol/acetone-fixed PTK-2 cells or A549 - human lung carcinoma cells
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 15-30 μg/mL using human skin
immunohistochemistry (frozen sections): suitable
microarray: suitable
western blot: suitable

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

相关类别

一般說明

Monoclonal Anti-Cytokeratin, pan (mouse IgG1 isotype) is derived from the C-11 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431. Cytokeratin is a member of the intermediate filaments family.

應用

Monoclonal Anti-Cytokeratin pan antibody has been used in immunoblotting, dot blot, immunohistochemistry, immunocytochemistry, immunofluorescence, immunostaining, detecting micro-metastases in lymph nodes, bone marrow, and other tissues and for determining the origin of poorly differentiated tumors.

生化/生理作用

Cytokeratin plays a major role in observing carcinomas.

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Spatio-temporal expression of MMP-2, MMP-9 and tissue kallikrein in uteroplacental units of the pregnant guinea-pig (Cavia porcellus)
Corthorn J, et al.
Reproductive Biology and Endocrinology, 5(1), 27-27 (2007)
Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients
Ausch C, et al.
European Journal of Surgical Oncology, 35(11), 1164-1168 (2009)
Gloria Valdés et al.
Reproductive sciences (Thousand Oaks, Calif.), 27(8), 1648-1655 (2020-05-21)
The pleiotropic kininogen-kallikrein-kinin system is upregulated in pregnancy and localizes in the uteroplacental unit. To identify the systemic and local participation of the bradykinin type 2 receptor (B2R), this was antagonized by Bradyzide (BDZ) during 2 periods: from days 20
Aminah Ali Abid Al-Juboori et al.
Proteomics, 19(21-22), e1800448-e1800448 (2019-03-14)
Epithelial and stromal communications are essential for normal uterine functions and their dysregulation contributes to the pathogenesis of many diseases including infertility, endometriosis, and cancer. Although many studies have highlighted the advantages of culturing cells in 3D compared to the
Utero-placental expression of angiotensin-(1-7) and ACE2 in the pregnant guinea-pig
Valdes G, et al.
Reproductive Biology and Endocrinology, 11(1), 5-5 (2013)

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