O9764

Anti-OTUB1 (57-70) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-HSPC263, Anti-OTB1, Anti-OTU1, Anti-Otubain 1
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 200
• 偶联物: unconjugated
• 抗体形式: IgG fraction of antiserum
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: antigen ~31 kDa
• 种属反应性: human
• 技术: western blot: 1:500-1:2,000
• UniProt登记号: Q96FW1
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... OTUB1(55611)

说明

一般描述

OTUB1 (OTU domain-containing ubiquitin aldehyde binding protein 1), a deubiquitinating enzyme (DUB) is a member of the ovarian tumor (OTU) domain protease superfamily. It is expressed in kidney, intestine, brain, liver and lung. This gene is located on human chromosome 11q13.1.

免疫原

synthetic peptide corresponding to amino acids 57-70 of human OTUB1

应用

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

生化/生理作用

OTUB1 (OTU domain-containing ubiquitin aldehyde binding protein 1) expression helps to predict the prognosis of hepatocellular carcinoma (HCC) in patients. It can control the T-cell anergy by improving the degradation of the E3 ligase gene related to anergy in lymphocytes (GRAIL).

外形

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.