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Merck

N7627

Sigma-Aldrich

L -正缬氨酸

≥99% (TLC)

别名:

( S )-(+)-2-氨基戊酸, ( S )-2-氨基戊酸

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About This Item

线性分子式:
CH3CH2CH2CH(NH2)CO2H
CAS号:
分子量:
117.15
Beilstein:
1721162
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

产品名称

L -正缬氨酸, arginase inhibitor

品質等級

化驗

≥99% (TLC)

形狀

powder

顏色

white

mp

>300 °C (lit.)

應用

detection

SMILES 字串

CCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI 密鑰

SNDPXSYFESPGGJ-BYPYZUCNSA-N

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應用


  • 纳米药物介导TAM相关精氨酸代谢干扰,促进光动力免疫治疗。:该研究探讨了使用纳米药物干扰肿瘤相关巨噬细胞(TAM)的精氨酸代谢,增强光动力免疫治疗的疗效。L-正缬氨酸在这种代谢干扰中起着至关重要的作用(Chen et al., 2024)。

生化/生理作用

L-正缬氨酸增强活化巨噬细胞产生 NO。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C I Chang et al.
The American journal of physiology, 274(1 Pt 2), H342-H348 (1998-02-12)
In macrophages and many other cell types, L-arginine is used as a substrate by both nitric oxide synthase (NOS) and arginase to produce nitric oxide (NO) and urea, respectively. Because the availability of L-arginine is a major determinant for NO
Ying-Chen Lin et al.
The New phytologist, 223(4), 1904-1917 (2019-05-16)
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the biosynthesis of a primary phospholipid phosphatidylcholine. However, the primary choline kinase and its role in plant growth remained elusive in seed plants. Here
Seyed Abdollah Hosseini et al.
International journal of molecular sciences, 20(4) (2019-03-01)
The importance of magnesium (Mg) for plant growth is well-documented. Silicon (Si)-mediated alleviation of mineral deficiencies has been also reported in a number of plant species; however, there is no report on the relevance of Si nutrition in plants grown
Nelson Machado et al.
Journal of the science of food and agriculture, 97(13), 4295-4305 (2017-03-10)
Freezing represents a common conservation practice regarding vegetal foodstuffs. Since compositional features need to be monitored during storage, the development of rapid monitoring tools suitable for assessing nutritional characteristics arises as a pertinent issue. In this study, cowpea (Vigna unguiculata
Megan L Matthews et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(42), 17723-17728 (2009-10-10)
The alpha-ketoglutarate-dependent hydroxylases and halogenases employ similar reaction mechanisms involving hydrogen-abstracting Fe(IV)-oxo (ferryl) intermediates. In the halogenases, the carboxylate residue from the His(2)(Asp/Glu)(1) "facial triad" of iron ligands found in the hydroxylases is replaced by alanine, and a halide ion

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