推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
fractionated antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human
技术
Ouchterlony double diffusion: suitable
western blot: 1:2,000
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... NGF(4803)
mouse ... Ngf(18049)
一般描述
神经生长因子(NGF)属于神经营养蛋白家族。它位于人类染色体上的1p13.2。NGF有两种分子形式，即7S NGF和2.5S NGF，它们对神经元具有相同的神经营养作用。
特异性
可用于监测NGF（2.5S、β和7S）。
免疫原
来自雄性小鼠颌下腺的NGF-2.5S。
应用
抗神经生长因子2.5S抗体可用于免疫印迹和斑点印迹，最低抗体工作稀释度为1:2000。使用大鼠中缝大核组织提取物将1:1000的抗体稀释液用于免疫印迹。该抗体用于小鼠星形胶质细胞的免疫荧光和中和测定。
生化/生理作用
该基因的突变导致遗传性感觉和自主神经病变第五类（HSAN-V）。
外形
磷酸盐缓冲盐水溶液。
免责声明
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
其他客户在看
Micaela Caserta et al.
Frontiers in neuroscience, 13, 58-58 (2019-02-23)
Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). Yet, no study that we are aware of has examined their change as a function of different training paradigms. In addition, the
7S nerve growth factor has different biological activity from 2.5 S nerve growth factor in vitro
Shao N, et al.
Brain Research, 609(1-2), 338-340 (1993)
Liang-Wei Chen et al.
The Journal of comparative neurology, 497(6), 898-909 (2006-06-28)
To address the hypothesis that reactive astrocytes in the basal ganglia of an animal model of Parkinson's disease serve neurotrophic roles, we studied the expression pattern of neurotrophic factors in the basal ganglia of C57/Bl mice that had been treated
New protein fold revealed by a 2.3-
McDonald N Q, et al.
Nature, 354(6352), 411-411 (1991)
Anna R Taylor et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(3), 634-644 (2007-01-20)
During development, motoneurons (MNs) undergo a highly stereotyped, temporally and spatially defined period of programmed cell death (PCD), the result of which is the loss of 40-50% of the original neuronal population. Those MNs that survive are thought to reflect
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