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Merck

M6014

Sigma-Aldrich

Met-Leu-Phe acetate salt

≥97% (HPLC)

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About This Item

经验公式(希尔记法):
C20H31N3O4S
CAS号:
分子量:
409.54
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

化驗

≥97% (HPLC)

儲存溫度

−20°C

SMILES 字串

CSCCC(N)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(O)=O

InChI

1S/C20H31N3O4S/c1-13(2)11-16(22-18(24)15(21)9-10-28-3)19(25)23-17(20(26)27)12-14-7-5-4-6-8-14/h4-8,13,15-17H,9-12,21H2,1-3H3,(H,22,24)(H,23,25)(H,26,27)

InChI 密鑰

CHDYFPCQVUOJEB-UHFFFAOYSA-N

品質

Exhibits very weak chemotactic properties.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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G Banerjee et al.
Antimicrobial agents and chemotherapy, 42(2), 348-351 (1998-04-04)
The interaction of chemotactic peptide (e.g., fMet-Leu-Phe)-grafted liposomes with macrophages is noted to be rapid and specific. At a grafted peptide concentration of 100 nmol, internalization of the peptide-grafted liposomes by the macrophages is found to reach equilibrium in 30
Laurent Camous et al.
Blood, 117(4), 1340-1349 (2010-11-11)
Complement alternative pathway plays an important, but not clearly understood, role in neutrophil-mediated diseases. We here show that neutrophils themselves activate complement when stimulated by cytokines or coagulation-derived factors. In whole blood, tumor necrosis factor/formyl-methionyl-leucyl-phenylalanine or phorbol myristate acetate resulted
H L Nurcombe et al.
Annals of the rheumatic diseases, 48(1), 56-62 (1989-01-01)
Activated polymorphonuclear leucocytes (neutrophils) can generate both intracellular and extracellular luminol dependent chemiluminescence. As luminol dependent chemiluminescence largely measures the activity of the myeloperoxidase-H2O2 system, and as the extracellular activity of this enzyme may be responsible for the tissue damage
Didier G Ebo et al.
Journal of immunological methods, 375(1-2), 30-38 (2011-09-29)
Stimulated human basophils exhibit different degranulation patterns with release of mediators and appearance of activation markers such as CD63 and CD203c. Traditionally, released mediators are quantified in the supernatant of activated cells, whereas the expression of activation markers by individual
W Tao et al.
The Biochemical journal, 257(3), 633-637 (1989-02-01)
[3H]Arachidonic acid is released after stimulation of rabbit neutrophils with fMet-Leu-Phe or platelet-activating factor (PAF). The release is rapid and dose-dependent, and is inhibited in phorbol 12-myristate 13-acetate (PMA)-treated rabbit neutrophils. The protein kinase C (PKC) inhibitor 1-(5-isoquinoline-sulphonyl)-2-methylpiperazine (H-7) prevents

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