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Merck
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文件

I9759

Sigma-Aldrich

L-异亮氨酰-L-脯氨酰-L-异亮氨酸

≥97% (HPLC)

别名:

抑二肽素 A

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About This Item

经验公式（希尔记法）:
C17H31N3O4
CAS号:
90614-48-5
分子量:
341.45
MDL號碼:
MFCD00038707
分類程式碼代碼:
51111800
PubChem物質ID:
24896160
NACRES:
NA.77

化驗

≥97% (HPLC)

形狀

powder

溶解度

water: 1 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(O)=O

InChI

1S/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)

InChI 密鑰

JNTMAZFVYNDPLB-UHFFFAOYSA-N

Amino Acid Sequence

Ile-Pro-Ile

應用

Ile-Pro-Ile 已被用作采血补充剂，用于测定激素 ，另外还用于稳定岛细胞培养物中的类胰升糖素肽1（GLP-1）。它还被用于抑制血清采集后促性腺激素抑制激素（GnIH）的分解。

生化／生理作用

二肽基肽酶 IV 的抑制剂。抑制 HIV-1 或 HIV-2 进入 T 淋巴母细胞样和单核细胞样细胞系。

特點和優勢

该化合物是受体分类及信号转导手册上神经肽酶页面上的特色化合物。想要浏览手册的其他页面， 请单击此处。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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F Samuel van Nierop et al.
Clinical nutrition (Edinburgh, Scotland), 36(6), 1615-1620 (2016-10-25)
Bile acids (BA) are pleiotropic hormones affecting glucose and lipid metabolism. The physiochemical properties of different BA species affect their enterohepatic dynamics and their affinity for bile acid receptors. The BA pool composition is altered in patients with type 2
Gemma Pujadas et al.
Molecular metabolism, 39, 101008-101008 (2020-05-12)
Glucose-dependent insulinotropic polypeptide (GIP) conveys information from ingested nutrients to peripheral tissues, signaling energy availability. The GIP Receptor (GIPR) is also expressed in the bone marrow, notably in cells of the myeloid lineage. However, the importance of gain and loss
Effect of gonadotropin-inhibitory hormone on luteinizing hormone secretion in humans
George JT, et al.
Clinical Endocrinology, 86(5), 731-738 (2017)
Pádraigín A Harnedy et al.
Food research international (Ottawa, Ont.), 106, 598-606 (2018-03-28)
Large quantities of low-value protein rich co-products, such as salmon skin and trimmings, are generated annually. These co-products can be upgraded to high-value functional ingredients. The aim of this study was to assess the antidiabetic potential of salmon skin gelatin
Pancreatic alpha cell-derived glucagon-related peptides are required for beta cell adaptation and glucose homeostasis
Traub S, et al.
Cell Reports, 18(13), 3192-3203 (2017)
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