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Merck
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主要文件

I4638

Sigma-Aldrich

Interleukin-1β Fragment 163-171 human

≥97% (HPLC), synthetic

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About This Item

经验公式(希尔记法):
C39H64N12O19
分子量:
1004.99
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:

生物源

synthetic

化驗

≥97% (HPLC)

形狀

powder

分子量

Mw 1004.99

包裝

pkg of 1 mg

顏色

white

溶解度

water: soluble 1 mg/mL, clear, colorless

UniProt登錄號

儲存溫度

−20°C

SMILES 字串

CC(C)[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(O)=O

InChI

1S/C39H64N12O19/c1-17(2)31(43)38(68)47-18(6-9-25(41)53)32(62)44-15-27(55)45-19(7-10-28(56)57)33(63)46-20(8-11-29(58)59)34(64)51-24(16-52)37(67)49-22(13-26(42)54)35(65)50-23(14-30(60)61)36(66)48-21(39(69)70)5-3-4-12-40/h17-24,31,52H,3-16,40,43H2,1-2H3,(H2,41,53)(H2,42,54)(H,44,62)(H,45,55)(H,46,63)(H,47,68)(H,48,66)(H,49,67)(H,50,65)(H,51,64)(H,56,57)(H,58,59)(H,60,61)(H,69,70)/t18-,19-,20-,21-,22-,23-,24-,31-/m0/s1

InChI 密鑰

NIXBZDOQHRZFDR-OEWCNXHOSA-N

基因資訊

human ... IL1B(3553)

Amino Acid Sequence

Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys

生化/生理作用

IL1B (interleukin 1 β) is an immune-activating cytokine. In presence of infection or cell stress, it gets converted into active mature form.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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G Antoni et al.
Journal of immunology (Baltimore, Md. : 1950), 137(10), 3201-3204 (1986-11-15)
Short peptide fragments of human and murine interleukin 1 (IL 1) were synthesized on the basis of their predicted exposure on the surface of the molecule in an attempt to identify the minimal structure responsible for the immunostimulatory activity of
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The Journal of surgical research, 172(1), e39-e46 (2011-11-15)
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L Nencioni et al.
Journal of immunology (Baltimore, Md. : 1950), 139(3), 800-804 (1987-08-01)
The stimulating effect of a synthetic nonapeptide (fragment 163-171) of human interleukin 1 beta (IL-1 beta) on antibody responses to both T helper-dependent and T helper-independent antigens was investigated. It was shown that the nonapeptide enhanced the antibody response, as
Anna K Blakney et al.
Journal of biomedical materials research. Part A, 100(6), 1375-1386 (2012-03-13)
Poly(ethylene glycol) (PEG) hydrogels, modified with RGD, are promising platforms for cell encapsulation and tissue engineering. While these hydrogels offer tunable mechanical properties, the extent of the host response may limit their in vivo applicability. The overall objective was to

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