跳转至内容
Merck
所有图片(3)

文件

I1286

Sigma-Aldrich

淫羊藿甙

≥94% (HPLC)

别名:

4′-O-甲基-8-γ，γ-dimethylallylkaempferol-3-鼠李糖苷素-7-葡糖苷

登录查看公司和协议定价
所有图片(3)

About This Item

经验公式（希尔记法）:
C33H40O15
CAS号:
489-32-7
分子量:
676.66
MDL號碼:
MFCD00210516
分類程式碼代碼:
12352205
PubChem物質ID:
329815347
NACRES:
NA.25

化驗

≥94% (HPLC)

顏色

light yellow to yellow

溶解度

DMSO: 50 mg/mL, clear, colorless to dark yellow

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

room temp

SMILES 字串

COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2

InChI

1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1

InChI 密鑰

TZJALUIVHRYQQB-XLRXWWTNSA-N

正在寻找类似产品? 访问 产品对比指南

相关类别

一般說明

淫羊藿苷是一种戊基化的黄酮醇，是淫羊藿中主要的生物活性化合物。

應用

淫羊藿苷已被用于：
  • 制备局部外用制剂，用于测定其对大鼠皮肤创面愈合的影响
  • 测试其对大鼠下背痛（LBP）的镇痛作用
  • 作为大鼠骨质疏松症的潜在疗法
  • 研究其对棕榈酸酯(PA)诱导的骨骼肌C2C12肌管中胰岛素抵抗的影响
  • 作为神经保护剂研究其对人神经母细胞瘤SK-N-MC细胞中淀粉样蛋白-β (Aβ)-诱导的神经元胰岛素抵抗的影响

生化／生理作用

淫羊藿苷是一种治疗神经退行性疾病和其他影响神经系统的疾病的有效神经保护剂。它在未受精的卵母细胞中诱导抗衰老特性，以对抗年龄相关损伤。淫羊藿苷具有抗炎和抗纤维化的特性，有助于保护慢性肾病(CKD)相关的小鼠肾纤维化模型。它还是一种很好的抗糖尿病和抗动脉粥样硬化药物。淫羊藿苷是一种有效的抗癌药物。
来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成，并表现出抗氧化活性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Dawei Zhang et al.
Biochimie, 94(12), 2514-2522 (2012-07-17)
Accumulating evidences suggest that Herba epimedii has the potential benefits against osteoporosis. However, previous studies were focused on the crude extract, total flavonoids (TF) and icariin (ICA), and the detailed molecular mechanisms of action and structure-activity relationship (SAR) remain unclear.
Bin Wu et al.
Journal of ethnopharmacology, 142(3), 746-753 (2012-06-13)
Icariin represents an important active component in Herba Epimedii, which is a famous Chinese herbal medicine that is widely used to treat some age-related diseases in oriental countries. The aim of this work was to investigate the effects of icariin
Hsin-An Chen et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 59, 152917-152917 (2019-04-13)
The pathology change of renal tubulointerstitial fibrosis is a critical feature of chronic kidney disease (CKD), regardless of the primary insults. The infiltration of inflammatory cells and the consecutive secretion of profibrotic factors are frequently and conspicuously observed during the
Feifei Tao et al.
Biochemical pharmacology, 85(6), 798-807 (2012-12-25)
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder in the intestine which involves overproduction of pro-inflammatory cytokines and excessive functions of inflammatory cells. However, current treatments for IBD may have potential adverse effects including steroid dependence, infections and lymphoma.
Jitian Li et al.
BioMed research international, 2020, 4670604-4670604 (2020-08-18)
To investigate whether icariin (ICA), a well-known medicine extracted from the stem and leaf of Epimedium brevicornum Maxim, had analgesic effect on lower back pain (LBP) in rats. In a puncture-induced LBP rat model, the severity of LBP was quantified
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门