I0514

异腈甲基膦酸二乙酯

>97% (GC)

• 别名: Isocyanomethylphosphonic acid diethyl ester
• 线性分子式: CNCH₂P(O)(OC₂H₅)₂
• CAS号: 41003-94-5
• 分子量: 177.14
• Beilstein: 4674920
• MDL號碼: MFCD00042951
• 分類程式碼代碼: 12352000

属性

• 化驗: >97% (GC)
• 折射率: n20/D 1.433 (lit.)
• bp: 84-87 °C/0.1 mmHg (lit.)
• 密度: 1.105 g/mL at 25 °C (lit.)
• 儲存溫度: 2-8°C
• SMILES 字串: CCOP(=O)(C[N+]#[C-])OCC
• InChI: 1S/C6H12NO3P/c1-4-9-11(8,6-7-3)10-5-2/h4-6H2,1-2H3
• InChI 密鑰: ICURVXBGGDVHDT-UHFFFAOYSA-N

说明

應用

Reactant for:

• Copper-catalyzed cycloaddition reactions
• Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase
• Synthesis of sterol analogs as antifungal agents against plant pathogens
• Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions
• The Passerini reaction

用于合成 α-氨基酸的膦酸类似物的前体。