跳转至内容
Merck

H9538

Sigma-Aldrich

HNE-DMA

hexane solution, ≥85% (GC)

别名:

(e)-4- 羟基壬烯醛-二甲氧基乙烷, 4-HNE-DMA

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C11H22O3
分子量:
202.29
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥85% (GC)

形狀

hexane solution

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CCCCCC(O)\C=C\C(OC)OC

InChI

1S/C11H22O3/c1-4-5-6-7-10(12)8-9-11(13-2)14-3/h8-12H,4-7H2,1-3H3/b9-8+

InChI 密鑰

ATGIHMSJAARJTF-CMDGGOBGSA-N

生化/生理作用

HNE 的稳定形式;有毒的自由基第二信使。

準備報告

要从 HNE-DMA 制备HNE:在室温下,通过温和的氮气流蒸发己烷。在 4°C 下,添加 1 ml (5 mg )或 0.4 ml (2 mg) 的1 mM低温 Hcl,搅拌 45 分钟或者盖上试剂瓶振荡 30 分钟。水解后,最初混浊的溶液变得几乎透明。现在该溶液的pH值为 ∼3,含∼5 mg (5 mg)或∼2 mg (2 mg)醛(HNE),并且至少可稳定存放24小时(如果保持在4°C)。在1 mL己烷溶液中加入6.8 mg HNE-DMA,水解后得到5 mg HNE。建议现配现用HNE溶液。

訊號詞

Danger

危險分類

Aquatic Chronic 2 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Inhalation - STOT SE 3

標靶器官

Central nervous system, Nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

-14.8 °F - closed cup

閃點(°C)

-26 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Héléna Alamil et al.
Toxicology letters, 331, 57-64 (2020-05-23)
Electrophilic compounds present in humans, originating from endogenous processes or pollutant exposures, pose a risk to health though their reaction with nucleophilic sites in protein and DNA. Among this chemical class, aldehydes are mainly present in indoor air and they
Thomas Van Hecke et al.
Foods (Basel, Switzerland), 10(11) (2021-11-28)
Oxidative reactions during cooking and gastrointestinal digestion of meat and fish lead to the formation of various lipid- and protein oxidation products, some of which are toxic. In the present study, it was investigated how the addition of 3% butter
Femke van Diggelen et al.
PloS one, 14(3), e0213663-e0213663 (2019-03-23)
Parkinson's Disease (PD) is a neurodegenerative disease for which there currently is no cure. Aggregation of the pre-synaptic protein α-synuclein (aSN) into oligomers (αSOs) is believed to play a key role in PD pathology, but little is known about αSO
Mutian Jia et al.
Nature immunology, 21(7), 727-735 (2020-06-17)
Stimulator-of-interferon genes (STING) is vital for sensing cytosolic DNA and initiating innate immune responses against microbial infection and tumors. Redox homeostasis is the balance of oxidative and reducing reactions present in all living systems. Yet, how the intracellular redox state
Wejdane El Manaa et al.
Autophagy, 17(12), 4363-4385 (2021-05-26)
Parkinson disease (PD)-affected brains show consistent endoplasmic reticulum (ER) stress and mitophagic dysfunctions. The mechanisms underlying these perturbations and how they are directly linked remain a matter of questions. XBP1 is a transcription factor activated upon ER stress after unconventional

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门