储存温度
2-8°C
SMILES字符串
CC1=CC(=O)Oc2c(C)c3oc(C)c(CO)c3cc12
生化/生理作用
一种已知可插入双链 DNA 的光敏剂。可用于定向诱变以及 DNA 结合蛋白与 DNA 的交联。
S S Sastry et al.
Biochemistry, 32(21), 5526-5538 (1993-06-01)
We have developed a technique for cross-linking DNA binding proteins to DNA using psoralen furanside monoadducts as photoaffinity probes and a continuous-wave argon ion laser (366 nm) as a light source. Several DNA binding proteins (T7 RNA polymerase, UvrB, single-stranded
P A Havre et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(16), 7879-7883 (1993-08-15)
Oligonucleotides can bind as third strands of DNA in a sequence-specific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Here we use a 10-base triplex-forming oligonucleotide linked to a psoralen derivative at its 5' end to achieve
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