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Merck
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文件

H4395

Sigma-Aldrich

N-Heptyl-5-Chloro-1-Naphthalenesulfonamide

powder

别名:

Protein kinase C activator, SC-10

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About This Item

经验公式（希尔记法）:
C17H22ClNO2S
CAS号:
102649-79-6
分子量:
339.88
MDL號碼:
MFCD00065545
分類程式碼代碼:
12171500

形狀

powder

顏色

white

溶解度

DMSO: 10 mM
ethanol: soluble

儲存溫度

−20°C

SMILES 字串

CCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12

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H Nishino et al.
Biochimica et biophysica acta, 889(2), 236-239 (1986-11-28)
N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide (SC-9) activated Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C). SC-9 acted as a substitute for phosphatidylserine, which is one of the endogenous factors in activating protein kinase C. SC-9 was also effective in regulating the physiological functions at the
M Ito et al.
Biochemistry, 25(15), 4179-4184 (1986-07-29)
Naphthalenesulfonamide derivatives were used to study the mechanism of regulation of Ca2+-dependent smooth muscle myosin light chain phosphorylation catalyzed by Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C) and myosin light chain kinase. Derivatives such as N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide (SC-9), with a hydrophobic

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