生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen ~35 kDa
物種活性
mouse, human
濃度
~1.0 mg/mL
技術
immunoprecipitation (IP): 1.5-3 μg using lysates of HEK-293T cells over-expressing human HOXD4
indirect immunofluorescence: 0.25-0.5 μg/mL using paraformaldehyde-fixed HEK-293T cells over-expressing human HOXD4
western blot: 0.5-1 μg/mL using mouse brain extract
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... HOXD4(3233)
一般說明
The Homeobox D4 (HOXD4) gene is localized in mesodermal tissues and the central nervous system (CNS). The HOXD4 gene is located on the human chromosome at 2q31.1.
特異性
Anti-HOXD4 (N-terminal) recognizes human and mouse- HOXD4 (also known as HOX-4B, HOX-5).
應用
Anti-HOXD4 (N-terminal) antibody produced in rabbit may be used in:
- immunoblotting
- immunoprecipitation
- immunofluorescence
生化／生理作用
The Homeobox D4 (HOXD4) gene participates in tumorigenesis of the central nervous system. This gene acts as a biomarker in the diagnosis of gliomas. HOXD4 is involved in the evolution of spine and dura mater. It also participates in the etiology and pathogenesis of spinal extradural arachnoid cyst (SEDAC).
外觀
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
儲存和穩定性
For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Xin-Wei Zhao et al.
Oncotarget, 8(70), 115657-115666 (2018-02-01)
HOX (homologous box) is known as the dominant gene of vertebrate growth and cell differentiation. Abnormal expression of HOX gene in various tumors has attracted the attention of scholars. As a component of HOX clusters, HOXD4 plays a controversial role
Hui Liu et al.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 25(1), 46-54 (2018-12-28)
Homeobox D4 (HOXD4) belongs to the homeobox (HOX) family, which plays a crucial role in the early embryo development and cell differentiation. The role of HOXD4 in human gastric adenocarcinoma has not been elucidated. In the present study, we aimed
Yoji Ogura et al.
PloS one, 10(11), e0142126-e0142126 (2015-11-07)
Spinal extradural arachnoid cyst (SEDAC) is a cyst in the spinal canal that protrudes into the epidural space from a defect in the dura mater and leads to neurological disturbances. We previously showed that familial SEDAC is caused by FOXC2
Mojgan Rastegar et al.
Molecular and cellular biology, 24(18), 8090-8103 (2004-09-02)
Hox genes are differentially expressed along the embryonic anteroposterior axis. We used chromatin immunoprecipitation to detect chromatin changes at the Hoxd4 locus during neurogenesis in P19 cells and embryonic day 8.0 (E8.0) and E10.5 mouse embryos. During Hoxd4 induction in
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