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Merck

GW22386

Sigma-Aldrich

Anti-MORF4 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human, mouse

製造商/商標名

Genway 15-288-22386

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MORF4(10934)

免疫原

Immunogen Sequence: GI # 6996928, sequence 1-235

應用

Anti-MORF4 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Morf4 is a member of a family of seven genes and is mapped on chromosomes 15 (4q33-q34.1). It is a positive regulators of cell division and interact with histone deacetylases and acetyltransferases. Morf4 functions in regulation of chromatin dynamics. The proteins that escapes degradation in the cytoplasm, is transported to the nucleus where it is functional.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Steven D Bryce et al.
Neoplasia (New York, N.Y.), 4(6), 544-550 (2002-10-31)
Human chromosome 4 was previously shown to elicit features of senescence when introduced into cell lines that map to complementation group B for senescence, including HeLa cells. Subsequently, a DNA segment encoding the pseudogene Mortality Factor 4 (MORF4) was shown
Meizhen Chen et al.
Annals of the New York Academy of Sciences, 1197, 134-141 (2010-06-12)
Cellular senescence is the dominant phenotype over immortality. In our studies to identify senescence-related genes, we cloned Morf4, which induced senescence in a subset of tumor cells. Morf4 is a member of a family of seven genes, and Morf-related genes
Kaoru Tominaga et al.
Experimental cell research, 316(1), 92-102 (2009-09-23)
After undergoing several rounds of divisions normal human fibroblasts enter a terminally non-dividing state referred to as cellular or replicative senescence. We cloned MORF4 (mortality factor on human chromosome 4), as a cellular senescence inducing gene that caused immortal cells

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