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Merck

GW22383A

Sigma-Aldrich

Anti-PNLIPRP2 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203

生物源

chicken

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human, rat, mouse

製造商/商標名

Genway 15-288-22383A

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... PNLIPRP2(5408)

免疫原

Immunogen Sequence: GI # 4885555, sequence 16-139
Recombinant pancreatic lipase-related protein 2

應用

Anti-PNLIPRP2 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

PNLIPRP2 (pancreatic lipase-related protein 2) is also know as PLRP2 . It can digest fats in human milk and formula. In mice, it is essential for fat digestion, and in humans, its role in fat digestion is unclear. IL-4 induces PLRP2 in cytotoxic T lymphocytes (CTLs). PLRP2 can help in killing tumor cells and is alone required for lipid-dependent cytotoxicity mediated by cytotoxic T lymphocytes (CTLs).

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Karin Johnson et al.
Pediatric research, 74(2), 127-132 (2013-06-05)
Dietary fats must be digested into fatty acids and monoacylglycerols prior to absorption. In adults, colipase-dependent pancreatic triglyceride lipase (PTL) contributes significantly to fat digestion. In newborn rodents and humans, the pancreas expresses low levels of PTL. In rodents, a
Bryce N Alves et al.
Cell biochemistry and function, 27(5), 296-308 (2009-06-24)
IL-4 induces a lipase, pancreatic lipase related protein 2 (PLRP2), in cytotoxic T lymphocytes (CTLs). Because PLRP2 in semen can mediate lipid-dependent toxicity to sperm, we questioned whether CTL-derived PLRP2 could support similar cytotoxicity toward tumor cells. Recombinant PLRP2 was
Xunjun Xiao et al.
The Journal of biological chemistry, 286(30), 26353-26363 (2011-06-10)
In newborn mice, PLRP2 is essential for fat digestion. In human infants, the role of PLRP2 in fat digestion is unclear, as it has poor activity against long-chain triglycerides in vitro. Also, many infants carry a genetic polymorphism resulting in

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