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产品名称
粒细胞巨噬细胞集落刺激因子 人, GM-CSF, recombinant, expressed in E. coli, suitable for cell culture
生物来源
human
质量水平
重组
expressed in E. coli
方案
≥98% (SDS-PAGE)
表单
lyophilized powder
效能
≤0.1 ng/mL EC50
分子量
14.6 kDa
包装
pkg of 4X5 μg
pkg of 5 μg
储存条件
avoid repeated freeze/thaw cycles
技术
cell culture | mammalian: suitable
杂质
≤1.000 EU/μg
颜色
white
溶解性
water: soluble 0.010 mL, clear, colorless
UniProt登记号
储存温度
−20°C
基因信息
human ... CSF2(1437) , CSF2(1437)
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相关类别
一般描述
基于蛋白质含量的包装尺寸
生化/生理作用
粒细胞-巨噬细胞集落刺激因子(GM-CSF)是一种粒细胞、巨噬细胞和嗜酸性粒细胞谱系中的细胞生长和分化因子。GM-CSF在极低浓度下刺激多潜能祖细胞集落形成，是造血祖细胞在所有分裂过程中存活和增殖的重要因素。 它还能刺激一些上皮细胞和破骨细胞的生长。GM-CSF由多种细胞类型（单核细胞、内皮细胞、T细胞、成纤维细胞、丝裂原刺激的B细胞和脂多糖刺激的巨噬细胞）产生。GM-CSF是一种含有128个氨基酸的单链糖蛋白，采用保守二硫键。 人类和小鼠GM-CSF共享约。序列同源性54%，不发生生物活性交叉反应。
外形
从 0.2μm 过滤的 10mM 柠檬酸钠溶液 (pH3.5) 中冻干。
分析说明
使用人 TF-1 细胞在培养物中检测人 GM-CSF 的增殖活性。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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