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一般說明
牛丙种球蛋白(BGG)是奶牛和其他牛类免疫系统的重要组成部分。BGG 存在于牛的血液中,主要用于生产疫苗、血清和诊断试剂等医疗制品。BGG 还可用于治疗乙肝等疾病,以及增强人类和其他动物的免疫力。
應用
牛γ-球蛋白已被用于研究富含蛋白质的透明质酸溶液的成分和pH变化,而这些会影响到人工关节的生物学特性。它也可通过直接生物传感器SPR免疫检测测定牛初乳和牛奶中的免疫球蛋白G。
牛γ-球蛋白已被用作免疫耐受机制研究中的一种免疫应激。
生化/生理作用
牛血清的γ-G球蛋白可通过阴离子交换色谱、免疫电泳、区域电泳、超速离心和木瓜蛋白酶消化产物分析而进行分类。它们具有与人血清相似成分类似的属性。这是通过以下方法确定的:凝胶过滤、免疫电泳、阴离子交换色谱、超速离心和巯基乙醇还原。快和慢γ-G球蛋白是根据电泳迁移率、色谱洗脱位置以及生物学活性(补体固定)差异而进行分类的。牛γ-A已被有条件的发现于血清和色谱部分的免疫电泳分析中。
準備報告
由 Cohn 组分 II、III 制备
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Rui Fang et al.
eLife, 11 (2022-01-21)
The ring-like ATPase complexes in the AAA+ family perform diverse cellular functions that require coordination between the conformational transitions of their individual ATPase subunits (Erzberger and Berger, 2006; Puchades et al., 2020). How the energy from ATP hydrolysis is captured
Harvey E Indyk et al.
Journal of AOAC International, 86(2), 386-393 (2003-05-02)
An automated biosensor surface-plasmon resonance-based assay was developed for the determination of immunoglobulin G (IgG) in bovine milk and colostrum with either goat or rabbit antibovine IgG or protein G used as detecting molecule. The method is configured as a
Marc-Olivier Montjovent et al.
Bioanalysis, 9(18), 1385-1393 (2017-09-29)
Recombinant glycoprotein produced in nonhuman mammalian cell lines can be modified with the immunogenic nonhuman sialic N-glycolylneuraminic acid (Neu5Gc). We describe here a validated method for detection of antidrug antibodies against both protein and Neu5Gc-containing glycan epitopes. An electrochemiluminescent method
T Kitano et al.
Journal of biomechanics, 34(8), 1031-1037 (2001-07-13)
The relationship between the coefficient of friction and pH value or protein constituents of lubricating fluid, together with viscosity, were studied within a bearing surface model for artificial joint, ultra-high molecular weight polyethylene (UHMWPE) against stainless steel (SUS), using a
Zijing Chen et al.
Genetics, 215(3), 713-728 (2020-05-22)
TRP channels function in many types of sensory receptor cells. Despite extensive analyses, an open question is whether there exists a family of auxiliary subunits, which could influence localization, trafficking, and function of TRP channels. Here, using Drosophila melanogaster, we
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