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Merck

G2386

Sigma-Aldrich

N-Glutaryl-Gly-Arg-7-amido-4-methylcoumarin hydrochloride

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About This Item

经验公式(希尔记法):
C23H30N6O7 · HCl
分子量:
538.98
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:

儲存溫度

−20°C

SMILES 字串

Cl.CC1=CC(=O)Oc2cc(NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)CCCC(O)=O)ccc12

基底

A fluorogenic substrate for urokinase.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates.
R Lottenberg et al.
Methods in enzymology, 80 Pt C, 341-361 (1981-01-01)
T Morita et al.
Journal of biochemistry, 82(5), 1495-1498 (1977-11-01)
Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-amino-4-methylcoumarin was determined fluorometrically. Of these peptides, the following were

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