描述
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產品線
MISSION®
形狀
lyophilized powder
esiRNA cDNA 標靶序列
TGGCAGTGAATGTGTACTCTACGTCAGTCACCAGTGATAACCTAAGTCGACATGACATGCTGGCTTGGATCAATGAATCTCTGCAGTTGAATCTGACAAAGATAGAACAGTTGTGTTCAGGGGCTGCATATTGTCAGTTTATGGACATGCTCTTCCCTGGATCCATTGCCTTGAAGAAAGTGAAATTCCAAGCTAAGCTAGAACATGAATATATCCAGAACTTCAAAATACTACAAGCAGGCTTCAAGAGGATGGGCGTTGACAAAATAATTCCTGTGGATAAATTAGTAAAAGGAAAATTTCAGGACAATTTTGAATTTGTTCAATGGTTCAAGAAGTTTTTTGATGCAAATTATGATGGAAAAGAGTATGATCCTGTAGCTGCCAGACAAGGTCAAGAAACTGCAGTGGCTC
Ensembl | 小鼠類登錄號
NCBI登錄號
運輸包裝
ambient
儲存溫度
−20°C
基因資訊
mouse ... MAPRE1(13589) , Mapre1(13589)
相关类别
一般說明
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律資訊
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
S-C Tien et al.
Oncogene, 33(22), 2938-2946 (2013-06-19)
Deregulation of Shp2, a non-receptor tyrosine phosphatase, causes hyperactivation of extracellular signal-regulated kinase (ERK), leading to growth abnormality. Here, we show that inhibition of RhoA-Dia is sufficient to upregulate ERK activation in epithelial cells. Oncogenic Shp2 expression attenuates RhoA-Dia signaling
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