描述
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產品線
MISSION®
形狀
lyophilized powder
esiRNA cDNA 標靶序列
CAGCTTTGAAATTTATAAAACATGGAGAAAACTAAAGAGAAAGCTGAGAGGATTCTTCTAGAGCCCTATAGGTACTTACTTCAGTTACCAGGTAAACAGGTGAGAAGCAAACTTTCACAGGCATTTAATCACTGGCTGAAAGTTCCAGAAGACAAGCTACAGATTATCATTGAAGTGACTGAAATGTTGCATAATGCCAGTTTACTCATTGATGATATTGAAGACAGTTCAAAGCTCCGACGTGGTTTCCCAGTGGCTCACAGCATCTATGGTGTCCCATCTGTCATTAATTCTGCCAATTACGTCTACTTCCTTGGACTGGAAAAAGTCTTAACCCTTGATCACCCGGATGCGGTGAAGCTTTTCACACGCCAGCTTCTGGAACTTCATCAGGGACAAGGCCTCGATATTTACTGGAGGGACACCTACACTTGTCCAACTGAAGAAGAATATAAAGCCATGGTGTTGCAGAAGACAGGTGGTTTGTTTGGATTAGCAGTAGGTCTTATGCAGCTG
Ensembl | 小鼠類登錄號
NCBI登錄號
運輸包裝
ambient
儲存溫度
−20°C
基因資訊
mouse ... GGPS1(14593) , Ggps1(14593)
一般說明
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律資訊
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Wei-Bo Chen et al.
FEBS letters, 589(10), 1119-1126 (2015-03-31)
GGPPS catalyses the expression of GGPP, a key protein in the mevalonate metabolic pathway. HMG-CoA reductase inhibitor statins can induce liver injury by inhibiting GGPP. However, the function of GGPPS in liver injury has not yet been revealed. In this
Weiwei Tao et al.
The Journal of biological chemistry, 290(33), 20086-20097 (2015-06-27)
Elevated circulating free fatty acid levels are important contributors to insulin resistance in the muscle and liver, but the underlying mechanisms require further elucidation. Here, we show that geranylgeranyl diphosphate synthase 1 (GGPPS), which is a branch point enzyme in
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