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Merck
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文件

EMU152291

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Anks1b

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

100

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GTGGCTGCTTTCTTTTCTTACCTGGAGATTGCACTGTGGTGGTGGCAAGGGAGAAATTAATGCCCACATGTTGAACTTAAGTCTTTTAAAGTTTAGCCCAGGTATCCCTACACTCCTTGTTCGAGTGACAAATCATTATAATATTCTTTCAAACAACTGTCATACCGAAATACCAAAGGCTATATTAGGTAAAACAGCAGACAGTATACATAGGATCAAGTAACCCTATTTATTTGTAATAGAATCCACCAAGGGGAAAGGATGCAAAATAAACTTAGAAGCATGAATGAAGTTAGGTGTGGGGTAGTCTGAATATCAGGCTAAGACTTCTGGTATTTATTCCTTAGGAAATGAGAAAAGCACAAAGGATTTGGGGCAGTTAAATGACATCATTGGAACTGGCCTTTCAGAGAATGAATGTGATAGAAACTGGTCATTGCATTTAGAAAACGTAATCCAATTTCATTGACCTTCTGTATGGCCTGCATCTTATTTGTATTCATCCTGTCT

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... ANKS1B(77531)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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S-C Tien et al.
Oncogene, 33(22), 2938-2946 (2013-06-19)
Deregulation of Shp2, a non-receptor tyrosine phosphatase, causes hyperactivation of extracellular signal-regulated kinase (ERK), leading to growth abnormality. Here, we show that inhibition of RhoA-Dia is sufficient to upregulate ERK activation in epithelial cells. Oncogenic Shp2 expression attenuates RhoA-Dia signaling

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