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Merck
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EMU003411

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Txnip

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

CATGAGGCCTGGAAACAAATATGAGTACAAGTTCGGCTTCGAGCTTCCTCAAGGGCCCCTGGGAACATCCTTTAAAGGAAAATATGGTTGCGTAGACTACTGGGTGAAGGCTTTTCTCGATCGTCCCAGCCAGCCAACTCAAGAGGCAAAGAAAAACTTCGAAGTGATGGATCTAGTGGATGTCAATACCCCTGACCTAATGGCACCAGTGTCTGCCAAAAAGGAGAAGAAAGTTTCCTGCATGTTCATTCCTGATGGACGTGTGTCAGTCTCTGCTCGAATTGACAGAAAAGGATTCTGTGAAGGTGATGACATCTCCATCCATGCTGACTTTGAGAACACGTGTTCCCGAATCGTGGTCCCCAAAGCGGCTATTGTGGCCCGACACACTTACCTTGCCAATGGC

Ensembl | 小鼠類登錄號

ENSMUSG00000038393

NCBI登錄號

NM_023719

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... TXNIP(56338) , Txnip(56338)

相关类别

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Lance A Thielen et al.
Cell metabolism, 32(3), 353-365 (2020-07-30)
Diabetes is characterized by hyperglycemia, loss of functional islet beta cell mass, deficiency of glucose-lowering insulin, and persistent alpha cell secretion of gluconeogenic glucagon. Still, no therapies that target these underlying processes are available. We therefore performed high-throughput screening of
Wei Li et al.
Current cancer drug targets, 14(4), 348-356 (2014-04-12)
Approximately 85% of pancreatic cancer patients suffer from glucose intolerance or even diabetes because high glucose levels can contribute to oxidative stress which promotes tumor development. As one of the reactive oxygen species (ROS)-regulating factors, thioredoxin-interacting protein (TXNIP), is involved

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