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Merck
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主要文件

EHU054231

Sigma-Aldrich

MISSION® esiRNA

targeting human BCL3

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About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

CTTCCTTCCTTCCCCATCTCCACCCGCCTTCCTGCCCTTTGCTGGGGTCCTCCGAGGCCCTGGCCGGCCGGTGCCCCCCTCCCCAGCTCCAGGAGGCAGCTGAGGGGGATGGGGGGGCAGATCTTGGACTCATGAGGAGGGGCCCCCCTGCCCTGTGGGGTCAACCCTTCTGGAAACTGTGAAGATCTCACTCTGCCCCCCCCCCCCATCTTCGGGACCAGGATTTGCACAGAAGCACATGCACCTACCCATACACCCCCTCTTCTGAGCACAGATGTTCCCCCATCTCGCTCCCTCCCAGGACTCTGACCCCAGCATTCTCAGGCACCAGTCCCTGTCCGGAATGCCACCCACATCTTCCATTTCCATGTCCCCTCCCAGAGCTGGTGGACCCAGGGAACAGCCACTCCCCTCCACTCTCTACCAGATAACTGAGGAGGGGAGAGGTG

基因组数据库 |人类登记号

ENSG00000069399

NCBI登记号

NM_005178

运输

ambient

储存温度

−20°C

基因信息

human ... BCL3(602) , BCL3(602)

一般描述

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
NJU
EWT
WNS
ACS
FQR

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Mikiko Tohyama et al.
European journal of immunology, 48(1), 168-179 (2017-09-14)
IL-22 induces STAT3 phosphorylation and mediates psoriasis-related gene expression. However, the signaling mechanism leading from pSTAT3 to the expression of these genes remains unclear. We focused on Bcl-3, which is induced by STAT3 activation and mediates gene expression. In cultured
SeungPil Yun et al.
Biomolecules & therapeutics, 26(5), 464-473 (2017-08-24)
Cripto is a small glycosylphosphatidylinositol-anchored signaling protein that can detach from the anchored membrane and stimulate proliferation, migration, differentiation, vascularization, and angiogenesis. In the present study, we demonstrated that Cripto positively affected proliferation and survival of mesenchymal stem cells (MSCs)
Kangsheng Tu et al.
Oncology reports, 35(4), 2382-2390 (2016-02-18)
Previous studies have demonstrated the aberrant expression and oncogenic role of B-cell CLL/lymphoma-3 (BCL-3) in human malignancies. However, the clinical significance of BCL-3 and its biological function in human hepatocellular carcinoma (HCC) remain unknown. In the present study, the expression
Xi Chen et al.
Cell death & disease, 7(12), e2508-e2508 (2016-12-03)
Transforming growth factor beta (TGFβ) signaling in breast cancer is selectively associated with pulmonary metastasis. However, the underlying mechanisms remain unclear. Here we show that Bcl-3, a member of the IκB family, serves as a critical regulator in TGFβ signaling
Junhaohui Huo et al.
Acta biochimica et biophysica Sinica, 50(11), 1141-1149 (2018-10-06)
Bcl-3 is an established oncogene in diverse malignant tumors. In this study, we investigated a dual role of Bcl-3 in BL1-subtype triple-negative breast cancer (TNBC). The BL1-subtype TNBC is featured by increasing cell cycle gene expression and the highest sensitivity
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