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Merck

E3256

Sigma-Aldrich

Edrophonium chloride

别名:

Ethyl(m-hydroxyphenyl)dimethylammonium chloride

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About This Item

经验公式(希尔记法):
C10H16ClNO
CAS号:
分子量:
201.69
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

SMILES 字串

[Cl-].CC[N+](C)(C)c1cccc(O)c1

InChI

1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H

InChI 密鑰

BXKDSDJJOVIHMX-UHFFFAOYSA-N

基因資訊

human ... ACHE(43)

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生化/生理作用

Acetycholinesterase inhibitor

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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James Rook et al.
Pediatric emergency care, 26(5), 374-375 (2010-05-11)
Myasthenia gravis is a rare, chronic, autoimmune disorder characterized by postsynaptic dysfunction at the neuromuscular junction. The disease affects more females than males. We describe the case of a 17-year-old female adolescent with recurrent episodes of dysarthria and dysphagia and
Mathilde M Triquigneaux et al.
The Biochemical journal, 448(1), 83-91 (2012-08-15)
The principal role of AChE (acetylcholinesterase) is termination of impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine. The active site of AChE is near the bottom of a long and narrow gorge lined with aromatic residues.
Yehonatan Sharabi et al.
Movement disorders : official journal of the Movement Disorder Society, 23(12), 1725-1732 (2008-07-29)
Patients with Parkinson's disease (PD) often have manifestations of autonomic failure. About 40% have neurogenic orthostatic hypotension (NOH), and among PD+NOH patients virtually all have evidence of cardiac sympathetic denervation; however, whether PD+NOH entails extra-cardiac noradrenergic denervation has been less
Yuu Yamazaki et al.
Internal medicine (Tokyo, Japan), 49(1), 69-72 (2010-01-05)
We describe a 52-year-old man with a history of increasing fatigability and gait disturbances that were first attributed to hypothyroidism. On examination, he had bilateral pseudo-internuclear ophthalmoplegia with weakness of adduction and abducting nystagmus. Convergence was also impaired and he
Shin J Oh et al.
Muscle & nerve, 39(3), 328-332 (2009-01-08)
Demographic, clinical, and laboratory features were compared in 235 white and African-American (AA) patients with myasthenia gravis (MG) at the University of Alabama at Birmingham Neuromuscular Disease Clinic from May 2003 to January 2008. Seventy nine percent of patients were

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