E1283

ERK2，活性，GST 标记 人

recombinant, expressed in E. coli, PRECISIO^® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 别名: ERT1, MAPK1, MAPK2, P41mapk, P42MAPK, PRKM1, PRKM2, p40, p47
• UNSPSC代码: 12352200
• NACRES: NA.32

属性

• 重组: expressed in E. coli
• 质量水平: 200
• 产品线: PRECISIO^® Kinase
• 方案: ≥70% (SDS-PAGE)
• 表单: buffered aqueous glycerol solution
• 比活: 613-829 nmol/min·mg
• 分子量: ~68 kDa
• UniProt登记号: P28482
• 运输: dry ice
• 储存温度: −70°C
• 基因信息: human ... MAPK1(5594)

说明

生化/生理作用

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable