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Merck

D0875

Sigma-Aldrich

Dansylglycine

fluorescent amino acid

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About This Item

经验公式(希尔记法):
C14H16N2O4S
CAS号:
分子量:
308.35
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.26

表单

powder

技术

ligand binding assay: suitable

储存温度

−20°C

SMILES字符串

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(O)=O

InChI

1S/C14H16N2O4S/c1-16(2)12-7-3-6-11-10(12)5-4-8-13(11)21(19,20)15-9-14(17)18/h3-8,15H,9H2,1-2H3,(H,17,18)

InChI key

QHFXORCWAQTTGH-UHFFFAOYSA-N

应用

Dansylglycine, an HSA drug site II probe, is used for the differentiation and analysis of specific binding sites on serum albumin. Dansylglycine is used to generate chromophore-modified cyclodextrins for use in chemosensor development.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T Tanabe et al.
Analytical chemistry, 73(13), 3126-3130 (2001-07-27)
Dansylglycine-modified cyclodextrin (DnsC4-beta-CD) was prepared as a fluorescent host that is capable of being immobilized on a cellulose membrane (DnsC4-beta-CD membrane). DnsC4-beta-CD immobilized on the cellulose membrane decreased its fluorescence intensity with increasing concentration of guest molecules, indicating that the
Eva A Enyedy et al.
Bioorganic & medicinal chemistry, 19(14), 4202-4210 (2011-06-24)
The specific binding of carrier ligands of antidiabetic vanadium(IV) and zinc(II) complexes into drug binding pockets of human serum albumin (HSA) has been investigated via displacement reactions of site markers such as warfarin and dansylglycine by different spectroscopic (fluorescence, circular
J Bramhall
Biochemistry, 25(13), 3958-3962 (1986-07-01)
The amphiphilic fluorescent dye N-[(5-dimethylamino)naphth-1-ylsulfonyl]glycine (dansylglycine) can be used to monitor the magnitude and stability of transmembrane proton gradients. Although freely soluble in aqueous media, the dye readily adsorbs to the surfaces of lipid vesicles. Because membrane-bound dye fluoresces at
Máté Kozsup et al.
Journal of inorganic biochemistry, 204, 110963-110963 (2019-12-25)
Four Co(III) ternary complexes with the composition of [(Co(4 N))2(quin)](ClO4)4 or [(Co(4 N))2(quinS)](ClO4)3, where 4 N = tris(2-aminoethyl)amine (tren) or tris(2-pyridylmethyl)amine (tpa), quinH2 = quinizarin (1,4-dihydroxy-9,10-anthraquinone), quinSH3 = quinizarin-2-sulfonic acid (1,4-dihydroxy-9,10-anthraquinone-2-sulfonic acid), were synthesized, characterized and their human serum albumin (HSA) binding capabilities were also tested. The complexes can
G M Robertz et al.
Klinische Wochenschrift, 61(13), 649-653 (1983-07-01)
Human serum albumin (HSA) was isolated and purified (greater than 97% purity) from normal sera, from sera of patients with severe chronic renal insufficiency and from sera to which a strongly protein bound acidic drug--clofibrinic acid--was added as a model

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