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化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
mp
180-183 °C (lit.)
溶解度
H2O: 5 mg/mL, clear
儲存溫度
room temp
SMILES 字串
CS(O)(=O)=O.Nc1ncnc2n(cnc12)C3CCCC3
InChI
1S/C10H13N5.CH4O3S/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7;1-5(2,3)4/h5-7H,1-4H2,(H2,11,12,13);1H3,(H,2,3,4)
InChI 密鑰
AJMDRSJHCYQPQI-UHFFFAOYSA-N
生化／生理作用
A stable, cell-permeable, non-competitive adenylyl cyclase inhibitor that targets the P-site domain. IC50 = 100 μM in detergent-dispersed rat brain preparation.
特點和優勢
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Yu Zhang et al.
Frontiers in neuroscience, 14, 364-364 (2020-05-16)
Electrical synapses between neurons exhibit a high degree of plasticity, which makes critical contributions to neuronal communication. The GABAergic parvalbumin-expressing (PV+) neurons in the thalamic reticular nucleus (TRN) interact with each other through electrical and chemical synapses. Plasticity of electrical
商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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