C2854

Caspase 2 human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution, >1000 units/mg protein

• 别名: Ich-1, Nedd2
• MDL號碼: MFCD02686998
• 分類程式碼代碼: 12352200

属性

• 重組細胞: expressed in E. coli
• 化驗: ≥95% (SDS-PAGE)
• 形狀: buffered aqueous solution
• 比活性: >1000 units/mg protein
• 分子量: inactive proenzyme 56 kDa (active form consists of 17 kDa and 10 kDa subunits); ≥30 kDa
• UniProt登錄號: P42575
• 儲存溫度: −20°C
• 基因資訊: human ... CASP2(835)

说明

生化／生理作用

Caspase 2 plays a major role in both positive and negative regulation of programmed cell death. It exists as two spliced variants, Ich-1L (long) and Ich-1S (short). Functionally, the two forms differ in that overexpression of the long form will induce apoptosis, while overexpression of the short form suppresses cell death.

單位定義

One unit will hydrolyze one nmol of N-Acetyl-Val-Asp-Val-Ala-Asp-AFC per min at pH 7.5 at 25 °C.

外觀

Solution in 25 mM HEPES, pH 7.5, 0.15 M NaCl, 5 mM dithiothreitol, 10% sucrose, with 0.5 mg bovine serum albumin

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable