B9928

Anti-Bone Morphogenetic Protein Receptor 2 antibody produced in goat

affinity isolated antibody, lyophilized powder

• 别名: Anti-BMP R2
• MDL编号: MFCD02095904
• UNSPSC代码: 51111800

属性

• 生物来源: goat
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: lyophilized powder
• 种属反应性: human
• 技术: indirect ELISA: 0.5-1.0 μg/mL; western blot: 0.1-0.2 μg/mL
• UniProt登记号: Q13873
• 储存温度: −20°C
• 基因信息: human ... BMPR2(659)

说明

一般描述

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage, hematopoietic cell formation and mesoderm patterning. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. Bone Morphogenetic Protein Receptor 2 (BMP R2) is a 70-80kD protein that belongs to serine/threonine kinases family. BMPs bind to BMP R2 and then recruits the transducing type I receptor which in turn activate the Smad protein signaling pathway. Anti-Bone Morphogenetic Protein Receptor 2 (BMP R2) antibody can be used in western blotting (working concentration:- 0.1-0.2 μg/mL). Goat anti-BMP R2 antibody reacts specifically with recombinant human BMP-R2. The antibody exhibits 10% (approx.) cross-reactivity with recombinant mouse BMP-RIB using reducing conditions and less than 1% cross-reactivity with recombinant mouse BMP-RIA and recombinant human BMP-RIA.

特异性

By immunoblotting (reducing conditions), the antibody shows 10% cross-reactivity with recombinant mouse BMP RIB and <1% cross-reactivity with recombinant human BMP RIA and recombinant mouse BMP RIA.

免疫原

recombinant human BMP R2 expressed in NSO cells.

应用

Anti-Bone Morphogenetic Protein Receptor 2 (BMP R2) antibody may be used in indirect ELISA at a working antibody concentration of 0.5-1.0 μg/ml.

外形

Lyophilized from solution in phosphate buffered saline containing 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.