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品質等級
化驗
≥90% (GC)
形狀
liquid
儲存溫度
2-8°C
InChI
1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3
InChI 密鑰
DIKPQFXYECAYPC-UHFFFAOYSA-N
應用
致癌物 N-丁基-N-(4-羟基丁基)亚硝胺(BBN)用于在动物模型中诱导病原学相关的侵袭性膀胱癌。
生化/生理作用
致癌物质用于在动物模型中诱导膀胱癌。暴露的结果在组织学上与人膀胱肿瘤发生相当。用于化学预防研究。
包裝
100 mL 血清瓶封装,配有丁基橡胶塞和铝质撕裂密封。
注意
通过注入任何相容的溶剂可在不暴露内容物的情况下制备任何所需强度的溶液。
重構
将内容物溶解在100mL溶剂中,可得到1%的溶液。
法律資訊
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Carc. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
296.6 °F
閃點(°C)
147 °C
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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We previously reported that the expression of CXC chemokine receptor-4 (CXCR4) was upregulated in invasive bladder cancers and that the small peptide T140 was a highly sensitive antagonist for CXCR4. In this study, we identified that CXCR4 expression was induced
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In the present study, effects of L-leucine and L-isoleucine on rat bladder carcinogenesis were investigated using AIN-93G and MF basal diet. In Experiment 1, N-butyl-N-(4-hydroxybutyl)-nitrosamine was used as an initiator of bladder carcinogenesis. In the AIN-93G diet groups, a significantly
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The present gold standard for bladder cancer is Mycobacterium bovis bacillus Calmette-Guérin (BCG) immunotherapy, but serious side-effects are common. We previously reported that C3H/HeN mice vaccinated with a mixture of MBT-2 cells and artificial BCG, octaarginine-modified liposomes incorporating the cell
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