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Merck
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文件

B170

Supelco

BW373U86 hydrochloride

powder

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About This Item

经验公式（希尔记法）:
C27H37N3O2 · HCl
CAS号:
155836-52-5
分子量:
472.06
MDL號碼:
MFCD01321040
分類程式碼代碼:
41116107

形狀

powder

技術

HPLC: suitable
gas chromatography (GC): suitable

顏色

tan

溶解度

H2O: 4 mg/mL

格式

neat

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化／生理作用

Potent, nonpeptide δ-opioid receptor agonist.

注意

Hygroscopic, store desiccated

法律資訊

Sold with the permission of Delta Pharmaceuticals Inc

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Ai Hashimoto et al.
Toxicologic pathology, 48(3), 509-523 (2020-01-04)
Macrophages and myofibroblasts are important in fibrogenesis. The cellular characteristics in pancreatic fibrosis remain to be investigated. Pancreatic fibrosis was induced in F344 rats by a single intravenous injection of dibutyltin dichloride. Histopathologically, the induced pancreatic fibrosis was divided into
K J Chang et al.
The Journal of pharmacology and experimental therapeutics, 267(2), 852-857 (1993-11-01)
Four different opioid receptor binding assays and three different isolated tissue studies were used to screen for delta receptor-selective nonpeptidic compounds. (+/-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-Allyl-2,5- dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide (BW373U86) was a potent delta receptor-selective ligand in receptor binding assays. The Ki values were 1.8 +/-
S D Comer et al.
The Journal of pharmacology and experimental therapeutics, 267(2), 866-874 (1993-11-01)
Several opioid agonists were evaluated in pigeons trained to discriminate i.m. injections of sterile water from either the mu agonist morphine (5.6 mg/kg), the kappa agonist bremazocine (0.032mg/kg) or (+/-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-allyl-2,5-dimethyl-1- piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide (BW373U86; 0.56 mg/kg). Pigeons were trained to peak one
S R Childers et al.
Molecular pharmacology, 44(4), 827-834 (1993-10-01)
BW373U86 is a potent and highly selective nonpeptidic agonist for delta-opioid receptors. To determine its ability to couple with G protein-linked second messenger systems, this study examined the effects of BW373U86 on the inhibition of adenylyl cyclase and the stimulation

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