A8344

Anti-ARC, C-Terminal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 别名: Anti-Apoptosis Repressor with CARD
• MDL编号: MFCD02095862
• UNSPSC代码: 12352203

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: antigen 22 kDa
• 种属反应性: human
• 技术: microarray: suitable; western blot: 1:1,000 using HeLa cell extract
• UniProt登记号: O60936
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... NOL3(8996)

说明

一般描述

ARC is part of the activity regulated cytoskeleton-associated protein family. It is involved in endocytosis of AMPA receptors and formation of long-term memory. It is found expressed in the cytoplasma of neuronal dendrites.

ARC protein contains an N-terminal CARD that has homology to the CARDs present in Apaf-1 and RAIDD. It binds to and inhibits the activity of caspase 8. It also binds to caspase 9 and to Ced-3. It inhibits apoptosis induced by death receptors that require caspase 8 activation.

Rabbit Anti-ARC, C-Terminal antibody binds to amino acids 191-208 of human ARC.

免疫原

synthetic peptide corresponding to amino acids 191-208 of human ARC (apoptosis repressor with CARD).

应用

Rabbit Anti-ARC, C-Terminal antibody can be used for western blot (1:1,000) and microarray analyses.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.