A7980

AC-41848 水合物

≥98% (HPLC), solid

• 别名: 1-[(2,4-Dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-5H-imidazo[1,2-a]azepinium bromide hydrate
• 经验公式（希尔记法）: C₂₁H₂₁BrCl₂N₂ · xH₂O
• CAS号: 400856-69-1
• 分子量: 452.21 (anhydrous basis)
• MDL编号: MFCD08705316
• UNSPSC代码: 12352200
• PubChem化学物质编号: 24724399
• NACRES: NA.77

属性

• 方案: ≥98% (HPLC)
• 表单: solid
• 储存条件: desiccated; under inert gas
• 溶解性: DMSO: ~14 mg/mL; H₂O: >5 mg/mL
• 储存温度: 2-8°C
• SMILES字符串: [Br-].[H]O[H].Clc1ccc(C[n+]2cc(-c3ccccc3)n4CCCCCc24)c(Cl)c1
• InChI: 1S/C21H21Cl2N2.BrH.H2O/c22-18-11-10-17(19(23)13-18)14-24-15-20(16-7-3-1-4-8-16)25-12-6-2-5-9-21(24)25;;/h1,3-4,7-8,10-11,13,15H,2,5-6,9,12,14H2;1H;1H2/q+1;;/p-1
• InChI key: FPOBEBBUBSFIIA-UHFFFAOYSA-M

说明

应用

AC-41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist.

生化/生理作用

AC-41848 is a potent, cell permeable, subtype selective retinoic acid receptor RARγ agonist. AC-41848 has high selectivity (92%) for RARγ. EC₅₀ = 5.9 μM.

Potent, cell permeable, subtype selective retinoic acid receptor RARγ agonist. High selectivity (92%) for RARγ. EC₅₀ = 5.9 μM.

特点和优势

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H315,H319,H335
• 预防措施声明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危险分类: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 靶器官: Respiratory system
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: dust mask type N95 (US), Eyeshields, Gloves