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Merck
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A6830

Sigma-Aldrich

8-Azido-cyclic adenosine diphosphate-ribose

≥95% (HPLC), lyophilized powder

别名:

Cyclic adenosine diphosphate-ribose 8-azide

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About This Item

经验公式（希尔记法）:
C15H20N8O13P2
CAS号:
150424-94-5
分子量:
582.31
MDL编号:
MFCD01310493
UNSPSC代码:
41106305
PubChem化学物质编号:
24891143

方案

≥95% (HPLC)

表单

lyophilized powder

储存温度

−20°C

SMILES字符串

O[C@H]1[C@@H](O)[C@H]2Nc3ncnc4[n@@H]([C@@H]5O[C@H](COP(=O)(OC[C@H]1O2)OP(O)(O)=O)[C@@H](O)[C@H]5O)c(N=[N+]=[N-])nc34

应用

Photoaffinity label

联系

Analog of cyclic ADP-ribose

外形

Lyophilized powder containing approx. 50% sodium chloride.

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Preparation of cyclic ADP-ribose antagonists and caged cyclic ADP-ribose.
T F Walseth et al.
Methods in enzymology, 280, 294-305 (1997-01-01)
T F Walseth et al.
The Journal of biological chemistry, 268(35), 26686-26691 (1993-12-15)
We have synthesized 8-azido-cyclic ADP-ribose (8N3-cADPR) and [32P]8-azido-cyclic ADP-ribose ([32P]8N3-cADPR) in order to characterize cyclic ADP-ribose-(cADPR) binding sites in sea urchin egg homogenates. 8N3-cADPR was an antagonist of cADPR since it did not induce Ca2+ release from egg microsomes but
T F Walseth et al.
Biochimica et biophysica acta, 1178(3), 235-242 (1993-09-13)
Cyclic ADP-ribose (cADPR) is a naturally-occurring metabolite of NAD+ that is as effective as inositol trisphosphate in mobilizing intracellular Ca2+. A series of analogs modified at the 8-position of the adenine group were synthesized for the investigation of the relationship

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