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Merck
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主要文件

A5356

Sigma-Aldrich

N-Me-Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide

≥96% (HPLC), lyophilized powder

别名:

N-Me-Abz-Amyloid β-Protein (37-44)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide

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About This Item

经验公式(希尔记法):
C70H116N26O18 · xC2HF3O2
分子量:
1609.83 (free base basis)
UNSPSC代码:
12352200
NACRES:
NA.32

方案

≥96% (HPLC)

表单

lyophilized powder

组成

Peptide content, 92% HPLC

溶解性

H2O: >1 mg/mL

运输

dry ice

储存温度

−20°C

Amino Acid Sequence

N-Me-Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2

生化/生理作用

A novel intramolecularly quenched fluorescent, presenilin-dependent substrate for assaying γ -secretase activity. It has been used for partial purification and characterization of γ-secretase from post-mortem human brain.
An intramolecularly quenched, fluorescent γ-secretase substrate.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Okay Saydam et al.
Molecular and cellular biology, 29(21), 5923-5940 (2009-08-26)
Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, are usually benign, and are frequently associated with neurofibromatosis type 2. Here, we define a typical human meningioma microRNA (miRNA) profile and

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