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Merck

A4689

Sigma-Aldrich

LS-Tetrasaccharide b

from human milk

别名:

α-NeuNAc-(2→6)-(β-D-Gal-[1→3])-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-Glc, LST b, N-Acetylneuramin-lacto-N-tetraose b sodium salt

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About This Item

经验公式(希尔记法):
C37H62N2O29
CAS号:
分子量:
998.88
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:

生物来源

human milk

方案

≥95% (pulsed amperometric detection, HPLC)

表单

powder

储存温度

−20°C

SMILES字符串

CC(=O)NC1C(O)CC(OCC2OC(OC3C(O)C(CO)OC(OC(C(O)CO)C(O)C(O)C=O)C3O)C(NC(C)=O)C(OC4OC(CO)C(O)C(O)C4O)C2O)(OC1C(O)C(O)CO)C(O)=O

InChI

1S/C37H62N2O29/c1-10(45)38-19-12(47)3-37(36(59)60,68-31(19)22(52)14(49)5-41)61-9-18-25(55)30(66-34-27(57)26(56)23(53)16(7-43)62-34)20(39-11(2)46)33(64-18)67-32-24(54)17(8-44)63-35(28(32)58)65-29(15(50)6-42)21(51)13(48)4-40/h4,12-35,41-44,47-58H,3,5-9H2,1-2H3,(H,38,45)(H,39,46)(H,59,60)

InChI key

SFMRPVLZMVJKGZ-UHFFFAOYSA-N

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sadaki Asakuma et al.
Bioscience, biotechnology, and biochemistry, 71(6), 1447-1451 (2007-06-26)
Sialyl oligosaccharides of human milk/colostrum are generally believed to be of biological significance, for example with respect to anti-adhesion of pathogenic organism, providing precursors for biosynthesis of brain, and so on. However, the levels of each of the sialyl oligosaccharides
H Kitagawa et al.
Journal of biochemistry, 110(4), 598-604 (1991-10-01)
We have determined the structures of six oligosaccharides isolated from human milk using a monoclonal antibody, MSW 113. The isolation involved affinity chromatography on a column of the immobilized monoclonal antibody and high-performance liquid chromatography. From the results of 500
H Kitagawa et al.
The Journal of biological chemistry, 265(9), 4859-4862 (1990-03-25)
The occurrence of two novel oligosaccharides in human milk was investigated. These oligosaccharides were purified by affinity chromatography on a column of an immobilized monoclonal antibody, MSW 113. Structural studies, involving 500-MHz 1H NMR spectroscopy and fast atom bombardment-mass spectrometry
Yuanwu Bao et al.
Analytical biochemistry, 370(2), 206-214 (2007-09-01)
The acidic oligosaccharides of human milk are predominantly sialyloligosaccharides. Pathogens that bind sialic acid-containing glycans on their host mucosal surfaces may be inhibited by human milk sialyloligosaccharides, but testing this hypothesis requires their reliable quantification in milk. Sialyloligosaccharides have been
Z Shen et al.
Analytical biochemistry, 279(1), 37-45 (2000-02-23)
Oligosaccharides in human milk inhibit enteric pathogens in vitro and in vivo. Neutral milk oligosaccharides vary among individuals and over the course of lactation. To study such variation in the acidic milk oligosaccharides, a sensitive, convenient, quantitative method is needed.

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