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方案
≥98%
表单
(Powder with Chunk(s) or Crystals with Chunk(s))
mp
128-131 °C (lit.)
SMILES字符串
CC(=O)NNc1ccccc1
InChI
1S/C8H10N2O/c1-7(11)9-10-8-5-3-2-4-6-8/h2-6,10H,1H3,(H,9,11)
InChI key
UICBCXONCUFSOI-UHFFFAOYSA-N
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应用
用于造血系统研究的 1-乙酰基-2-苯肼 (AcPhHZ) 可与氧合血红蛋白反应形成自由基，可用于诱导溶血性贫血。
生化/生理作用
乙酰苯肼（1-Acetyl-2-phenylhydrazine，AcPhHZ) 是一种用于实验动物模型的血管肿瘤引发剂。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
H Ohno et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 32(2), 269-277 (1996-08-01)
A previous study revealed that DQ-2511, a new gastroprokinetic drug, induced hemolytic anemia together with increased Heinz body formation, preceded by a marked decrease in erythrocyte reduced glutathione (GSH) content, after 2 weeks of dosing onward in dogs. In this
G Bartosz et al.
Clinica chimica acta; international journal of clinical chemistry, 198(3), 239-243 (1991-05-15)
Erythrocytes of Down syndrome patients, having increased activity of superoxide dismutase and glutathione peroxidase, showed a similar increase in intracellular proteolysis upon stimulation with 1 mmol/l phenylhydrazine than normal erythrocytes. There were no differences in the magnitude of Heinz body
Y Manabe et al.
The Journal of toxicological sciences, 25(3), 161-165 (2000-09-15)
In this study, a new simple method to measure erythrocyte fragility with stirring of diluted blood (stirring method) was introduced and evaluated with anemic rats given beta-acetylphenylhydrazine (APHZ) or clofibrate. APHZ at a dose of 40 mg/kg caused significant decreases
T Umenai et al.
The Tohoku journal of experimental medicine, 186(3), 181-191 (1999-05-29)
An increase in the number of erythroblasts can be seen to some extent in the bone marrow of rats in the early stage of experimentally induced hemolytic anemia prior to any elevation in the plasma erythropoietin (Epo) level. This observation
Li Jia et al.
Nutrition (Burbank, Los Angeles County, Calif.), 27(11-12), 1194-1201 (2011-05-31)
Whether a specific nutritional support promotes healing of aplastic anemia (AA) patients is still unclear. Therefore, we explored the potential of a high-nucleotide, arginine, and micronutrient nutritional supplement on the nutritional rehabilitation of AA mice. The BALB/c AA mice model
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