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A4330

Sigma-Aldrich

4'-氨甲基三氧沙林 盐酸盐

别名:

4＆＃8242;氨基甲基-4,5-＆＃8242;，8三甲基补骨脂 盐酸盐

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About This Item

经验公式（希尔记法）:
C15H15NO3 · HCl
CAS号:
62442-61-9
分子量:
293.75
MDL號碼:
MFCD00134837
分類程式碼代碼:
12352200
PubChem物質ID:
24890846
NACRES:
NA.77

形狀

powder

品質等級

200

溶解度

H2O: 1 mg/mL
DMSO: 2 mg/mL

儲存溫度

2-8°C

SMILES 字串

CC1=CC(=O)Oc2c(C)c3oc(C)c(CN)c3cc12

InChI

1S/C15H15NO3/c1-7-4-13(17)19-14-8(2)15-11(5-10(7)14)12(6-16)9(3)18-15/h4-5H,6,16H2,1-3H3

InChI 密鑰

WBIICVGYYRRURR-UHFFFAOYSA-N

應用

4'-盐酸氨甲基三氧沙林可灭活 DNA 和 RNA 病毒，包括 HIV-1。4'-盐酸氨甲基三氧沙林在紫外光照射下可与核酸共价结合。

生化／生理作用

4'-盐酸氨甲基三氧沙林用于通过核酸交联和紫外线照射灭活 DNA 和 RNA 病毒，包括 HIV-1。

特點和優勢

这种化合物是细胞凋亡研究的特色产品。 点击此处 ，发现更多特色细胞凋亡产品。访问sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子的信息。

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Carc. 2 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000371450
0000371450
0000303630
0000303630
0000180067

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M N Lubaki et al.
AIDS research and human retroviruses, 10(11), 1427-1431 (1994-11-01)
Studies have shown that cytolytic T lymphocyte (CTL) responses may be critical to the clearance of the early viremia in acute HIV-1 infection. It is likely that these cells play an important role in prolonging the asymptomatic phase of the
W A Saffran et al.
Mutation research, 274(1), 1-9 (1992-06-01)
Photoreaction with psoralen, a DNA-crosslinking reagent, induces mitotic recombination in the yeast Saccharomyces cerevisiae. Psoralen damage-induced recombination was studied with non-replicating plasmids, which transform yeast cells by undergoing recombination events with chromosomal DNA. When plasmid DNA was photoreacted with psoralen
M A Reynolds et al.
Bioconjugate chemistry, 3(5), 366-374 (1992-09-11)
A method is reported for conjugating an analog of 4'-(aminomethyl)-4,5',8- trimethylpsoralen to methylphophonate oligonucleotides. This method enables the psoralen moiety to be coupled to the phosphonate backbone between any two desired bases in a sequence. When hybridized to a target
W S Groene et al.
Journal of virological methods, 38(1), 93-102 (1992-07-01)
The use of the synthetic psoralen 4'-aminomethyl-4,5',8-trimethylpsoralen hydrochloride (AMT) is described for the inactivation of infectious rotavirus, a member of the viral family Reoviradae with a double-stranded RNA genome. This method not only provides complete inactivation of the virus but
H Du et al.
RNA (New York, N.Y.), 7(1), 133-142 (2001-02-24)
Base pairing between the 5' end of U1 snRNA and the conserved 5' splice site of pre-mRNA is important for commitment complex formation in vitro. However, the biochemical mechanisms by which pre-mRNA is initially recognized by the splicing machinery is
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