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生物源
mouse
共軛
alkaline phosphatase conjugate
抗體表格
purified from hybridoma cell culture
抗體產品種類
secondary antibodies
無性繁殖
MB-11, monoclonal
形狀
buffered aqueous glycerol solution
物種活性
human
技術
direct ELISA: 1:35,000
dot blot: 1:20,000 using 20 ng of human IgM/dot
dot blot: 1:30,000 using 20 ng of human IgM/dot (chemiluminescence)
同型
IgG2b
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
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一般說明
Human IgMs are the initial immunoglobulin isotypes that appear in blood in response to the first exposure to external antigens. IgMs have been implicated in CNS myelin repair and increased secretory IgM levels have been linked to rhino-conjunctivitis . Monoclonal Anti-Human IgM (μ-chain specific)-Alkaline Phosphatase antibody is specific for human IgM. The product does not react with human IgG, IgA or light chains.
Monoclonal Anti-Human IgM (mouse IgG2b isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
免疫原
Human IgM isolated from pooled normal human serum
應用
Anti-Human IgM (μ-chain specific)-Alkaline Phosphatase antibody purified from hybridoma cell culture has been used in immunocytochemistry and enzyme linked immunosorbent assay (ELISA)
外觀
Solution in 0.05 M Tris buffer, pH 8.0, containing 1 mM MgCl2, 1% bovine serum albumin, 50% glycerol and 15 mM sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis
Xu X, et al.
Disease models & mechanisms, 8(8), 831-842 (2015)
Ines Pree et al.
Journal of immunology (Baltimore, Md. : 1950), 179(8), 5309-5316 (2007-10-04)
Previously, we have constructed recombinant derivatives of the major birch pollen allergen, Bet v 1, with a more than 100-fold reduced ability to induce IgE-mediated allergic reactions. These derivatives differed from each other because the two recombinant Bet v 1
Johan Bours et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 243(5), 456-463 (2005-06-03)
With various methods, secretory immunoglobulin M (sIgM) was assessed in tears of patients with rhino-conjunctivitis. Tears were analyzed by microimmunoelectrophoresis (MIE), size-exclusion high-pressure liquid chromatography (SE-HPLC), sodium dodecyl sulphate (SDS) electrophoresis and isoelectric focusing. Only very small traces of serum
Ana Luísa Tomás et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 39(11), 2205-2209 (2020-06-20)
Interest in the detection of specific anti-Pneumocystis jirovecii antibodies has emerged as less-invasive alternative diagnostic approaches. Here is presented the performance of an ELISA based on a recombinant synthetic multi-epitope kexin 1 (Kex1) antigen of P. jirovecii, previously developed. Results
Sina Sarikhani et al.
Applied biochemistry and biotechnology, 162(5), 1249-1257 (2010-02-18)
As IgM is the first isotype of antibody which appears in blood after initial exposure to a foreign antigen in the pattern of primary response, detection, and quantification of this molecule in blood seems invaluable. To approach these goals, generation
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