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Merck
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Key Documents

A1139

Sigma-Aldrich

β-Alanine benzyl ester p-toluenesulfonate salt

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About This Item

经验公式(希尔记法):
C10H13NO2 · C7H8O3S
CAS号:
分子量:
351.42
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

化驗

≥98% (TLC)

形狀

powder

顏色

white

應用

peptide synthesis

儲存溫度

−20°C

SMILES 字串

Cc1ccc(cc1)S(O)(=O)=O.NCCC(=O)OCc2ccccc2

InChI

1S/C10H13NO2.C7H8O3S/c11-7-6-10(12)13-8-9-4-2-1-3-5-9;1-6-2-4-7(5-3-6)11(8,9)10/h1-5H,6-8,11H2;2-5H,1H3,(H,8,9,10)

InChI 密鑰

FRHWYVGCFUQMJR-UHFFFAOYSA-N

生化/生理作用

β-Alanine benzyl ester (β-Ala-OBzl) is used in the biochemical synthesis of β-alanyl peptides via aminopeptidase(s).

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jiro Arima et al.
Journal of biotechnology, 147(1), 52-58 (2010-03-23)
Synthesis of beta-alanine (beta-Ala) containing dipeptide using S9 aminopeptidase from Streptomyces thermocyaneoviolaceus NBRC14271 (S9AP-St) was demonstrated with beta-Ala-benzyl ester (-OBzl) and various L-aminoacyl derivatives. For synthesis of beta-Ala-containing dipeptide, beta-Ala-OBzl was used preferentially as the acyl donor for S9AP-St, producing
Jiro Arima et al.
Applied and environmental microbiology, 72(6), 4225-4231 (2006-06-06)
Dipeptide synthesis by aminopeptidase from Streptomyces septatus TH-2 (SSAP) was demonstrated using free amino acid as an acyl donor and aminoacyl methyl ester as an acyl acceptor in 98% methanol (MeOH). SSAP retained its activity after more than 100 h
Linda Clijsters et al.
Molecular cell, 74(6), 1264-1277 (2019-05-28)
E2F1, E2F2, and E2F3A, the three activators of the E2F family of transcription factors, are key regulators of the G1/S transition, promoting transcription of hundreds of genes critical for cell-cycle progression. We found that during late S and in G2
Lin Deng et al.
Molecular cell, 73(5), 915-929 (2019-03-09)
DNA replication errors generate complex chromosomal rearrangements and thereby contribute to tumorigenesis and other human diseases. One mechanism that triggers these errors is mitotic entry before the completion of DNA replication. To address how mitosis might affect DNA replication, we

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