化驗
≥95.0% (HPLC)
形狀
powder
溶解度
water: 5 mg/mL, clear, colorless
儲存溫度
2-8°C
SMILES 字串
CC(O)=O.NC(=N)NCCC[C@H](NC(=O)CNC(=O)CCNC(=O)c1ccccc1)C(=O)Nc2ccc(cc2)[N+]([O-])=O
InChI
1S/C24H30N8O6.C2H4O2/c25-24(26)28-13-4-7-19(23(36)30-17-8-10-18(11-9-17)32(37)38)31-21(34)15-29-20(33)12-14-27-22(35)16-5-2-1-3-6-16;1-2(3)4/h1-3,5-6,8-11,19H,4,7,12-15H2,(H,27,35)(H,29,33)(H,30,36)(H,31,34)(H4,25,26,28);1H3,(H,3,4)/t19-;/m0./s1
InChI 密鑰
LNYCMHUMNWBNSM-FYZYNONXSA-N
應用
Pefachrome® substrates are used for chromogenic assays of various serine proteinases. Pefachrome® uPA is used for the detection of serine proteases such as urokinase-type plasminogen activator (urokinase).
包裝
1 piece contains 10 μmol Pefachrome® uPA and 20 mg glycine
其他說明
Chromogenic substrate test for the detection of urokinase in Shigella
法律資訊
Pefachrome is a registered trademark of Pentapharm AG, Basel
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Rong Pan et al.
The Journal of biological chemistry, 285(30), 22950-22956 (2010-05-21)
Enzymatic catalysis of biochemical reactions is essential to all living systems. The "lock and key" and "induced fit" models were early contributions to our understanding of the mechanisms involved in the reaction between an enzyme and its substrate. However, whether
M F Massenti et al.
Microbiologica, 10(3), 331-333 (1987-07-01)
A simple test for detection of urokinase in Shigella is described. The test is performed by suspending a loopful of bacteria in 100 microliters of a buffered 1mM solution of benzoyl-beta-alanyl glycyl-arginyl-4-nitroanilide acetate (Chromozym U). Enzymatic activity is revealed by
Urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9 (MMP-9) expression and activity during early embryo development in the cow.
Whiteside EJ, Kan M, Jackson MM, et al.
Anat. Embryol., 204, 477-483 (2001)
Yukari Yamamoto et al.
Journal of dermatological science, 47(2), 119-125 (2007-05-29)
Although pemphigus vulgaris (PV)-IgG has been shown to activate urokinase plasminogen activator (uPA) in cultured keratinocytes, activation of uPA is thought to have no primary role in PV-acantholysis, because PV-IgG is still pathogenic in uPA- and tissue-PA-knockout mice. To determine
D H Rhoney et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 56(20), 2047-2051 (1999-11-30)
The retention of urokinase activity after frozen storage was studied. Urokinase powder was reconstituted aseptically in sterile water for injection or preservative-free 0.9% sodium chloride injection to a final concentration of 5000 IU/mL. Samples were stored in 5-mL plastic syringes
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