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Merck

76437

Sigma-Aldrich

五甘醇单十二烷基醚

BioXtra, ≥98.0% (GC)

别名:

C12E5, 十二烷基五乙二醇醚, 十二烷基五甘醇, 聚氧乙烯(5)月桂基醚

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About This Item

线性分子式:
CH3(CH2)11(OCH2CH2)5OH
CAS号:
分子量:
406.60
Beilstein:
1797921
EC號碼:
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.25

描述

non-ionic

品質等級

產品線

BioXtra

化驗

≥98.0% (GC)

形狀

semisolid

分子量

406.60 g/mol

技術

drug transporter assay: suitable

密度

0.963 g/mL at 20 °C (lit.)

正離子痕跡

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES 字串

CCCCCCCCCCCCOCCOCCOCCOCCOCCO

InChI

1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3

InChI 密鑰

LAPRIVJANDLWOK-UHFFFAOYSA-N

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應用

<ul>
<li><strong>单克隆抗体和非离子表面活性剂在SiO(2)/水界面上的共吸附:</strong>本研究证明了五乙二醇单十二烷基醚与单克隆抗体的共吸附特性,对于生物制药制剂提高药物稳定性和递送具有重要意义(Lu et al., 2018)。</li>
<li><strong>使用水溶性表面活性剂添加剂对疏水性聚合物进行防水表面改性:</strong>本研究表明,五乙二醇单十二烷基醚能够对疏水性聚合物表面进行改性,使其具有防水性,指出了其在各种工业和涂料应用中的实用性(Thompson et al., 2021)。</li>
<li><strong>温度和盐度在非离子表面活性剂包覆二氧化硅纳米颗粒聚集中的协同作用:</strong>重点介绍了五乙二醇单十二烷基醚在纳米颗粒稳定方面的应用,特别是在不同的温度和盐度条件下,有助于定制药物递送系统和环境应用(Bharti et al., 2023)。</li>
</ul>

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象形圖

CorrosionExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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U Sivars et al.
Journal of chromatography. B, Biomedical applications, 680(1-2), 43-53 (1996-05-17)
The study includes partitioning of proteins in aqueous two-phase systems consisting of the polymer dextran and the non-ionic surfactant C12E5 (pentaethylene glycol mono-n-dodecyl ether). In this system a micelle-enriched phase is in equilibrium with a polymer-enriched phase. Charges can be
S Bulut et al.
The European physical journal. E, Soft matter, 27(3), 261-273 (2008-10-31)
We present a comprehensive study of the concentration-induced growth of nonionic wormlike micelles in dilute solutions, below the overlap concentration, where we combine static and dynamic light scattering and NMR self-diffusion. The data are analyzed in detail in terms of
Tiago Mendes Ferreira et al.
Physical chemistry chemical physics : PCCP, 10(39), 6033-6038 (2008-10-01)
A lyotropic nonionic lamellar system composed of pentaethyleneglycol mono n-dodecyl ether and D(2)O was studied using natural abundance (13)C NMR under magic-angle spinning. Applying a two-dimensional recoupling method proposed by Dvinskikh (R-PDLF), (1)H-(13)C dipolar couplings were estimated over a range
K Selber et al.
Bioseparation, 10(4-5), 229-236 (2002-09-18)
The parameters important for an optimisation of cloud point extraction in technical scale were investigated using a genetically engineered fusion protein derived from endoglucanase I expressed in Trichoderma reesei and the nonionic polyoxyethylene Agrimul NRE 1205. The key parameters are
Venkatraman Ramanujam et al.
Frontiers in chemistry, 7, 889-889 (2020-02-11)
Disulfide bridges in proteins are formed by the oxidation of pairs of cysteine residues. These cross-links play a critical role in stabilizing the 3D-structure of small disulfide rich polypeptides such as hormones and venom toxins. The arrangement of the multiple

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