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Merck

72559

Sigma-Aldrich

次氮基三乙酸

BioUltra, ≥99.0% (T)

别名:

N,N-二(羧甲基)甘氨酸, NTA, 三(羧甲基)胺

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About This Item

线性分子式:
N(CH2COOH)3
CAS号:
分子量:
191.14
Beilstein:
1710776
EC號碼:
MDL號碼:
分類程式碼代碼:
12352102
PubChem物質ID:
NACRES:
NA.25

產品線

BioUltra

品質等級

化驗

≥99.0% (T)

形狀

powder

反應適用性

reagent type: reductant

雜質

insoluble matter, passes filter test

燃燒殘留物

≤0.05%

損耗

≤0.1% loss on drying, 110 °C

pH值

1.7-2.7 (23 °C, 10 g/L)

mp

245 °C (dec.) (lit.)

溶解度

0.1 M NaOH: 0.1 M at 20 °C, clear, colorless

負離子痕跡

chloride (Cl-): ≤100 mg/kg

正離子痕跡

Al: ≤20 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤20 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

&lambda ;

0.1 M in 1 M NaOH

紫外吸收

λ: 260 nm Amax: 1.5
λ: 280 nm Amax: 0.05

SMILES 字串

OC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

InChI 密鑰

MGFYIUFZLHCRTH-UHFFFAOYSA-N

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應用

Nitrilotriacetic has been used in the preparation of nitrilotriacetic (NTA) solution for Ni-NTA slide generation.
一种优质的螯合剂。

生化/生理作用

Nitrilotriacetic (NTA) has the ability to link with histidine side chain of proteins. It can be used in fluorescent labelling, hexahistidine (His6)-tagged proteins for purification and surface immobilization.

其他說明

Chelating agent; As Pb2+ buffer, preparation and properties; In a mixture of Ca2+-buffering ligands; Encapsulation of radioactive metal ions in liposomes; Compilation and critical evaluation by IUPAC of published data on stability constants of NTA complexes in solution.

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

212.0 °F - closed cup

閃點(°C)

100 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


分析证书(COA)

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H.A. Mottola
Toxicol. Environm. Chem. Rev., 2, 99-99 (1974)
K J Hwang et al.
Biochimica et biophysica acta, 716(1), 101-109 (1982-05-05)
The encapsulation of radioactive metalic cations, such as 111In3+ or 67Ga3+, in the internal aqueous compartment of liposomes can be achieved with an efficiency of about 90%. The efficient loading of a high specific activity of cations into liposomes involves
Multivalent and flexible PEG-nitrilotriacetic acid derivatives for non-covalent protein pegylation
Mero AI, et al.
Pharmaceutical Research, 28(10), 2412-2412 (2011)
F.A. Simon et al.
Journal of Bioenergetics and Biomembranes, 16, 506-506 (1984)
G. Anderegg
Pure and Applied Chemistry. Chimie Pure Et Appliquee, 54, 2693-2693 (1982)

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