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Merck
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文件

56189

Sigma-Aldrich

羟苯基丙酸 N-羟基琥珀酰亚胺酯

≥97.0% (C), BioReagent

别名:

N-[(4-羟基氢化肉桂酰基)氧基]琥珀酰亚胺, N-琥珀酰亚胺 3-(4-羟基苯基)丙酸酯, Bolton-Hunter 试剂前体, Rudinger 试剂, SHPP

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About This Item

经验公式（希尔记法）:
C13H13NO5
CAS号:
34071-95-9
分子量:
263.25
Beilstein:
1545011
EC號碼:
251-818-1
MDL號碼:
MFCD00005515
分類程式碼代碼:
12352106
PubChem物質ID:
57651567
NACRES:
NA.25

product name

羟苯基丙酸 N-羟基琥珀酰亚胺酯, suitable for fluorescence, BioReagent, ≥97.0% (C)

產品線

BioReagent

化驗

≥97.0% (C)

mp

132-133 °C (lit.)

螢光

λex 320 nm; λem 409 nm in 0.1 M Tris pH 8.8, 2 mM H2O2, peroxidase

適合性

suitable for fluorescence

儲存溫度

−20°C

SMILES 字串

Oc1ccc(CCC(=O)ON2C(=O)CCC2=O)cc1

InChI

1S/C13H13NO5/c15-10-4-1-9(2-5-10)3-8-13(18)19-14-11(16)6-7-12(14)17/h1-2,4-5,15H,3,6-8H2

InChI 密鑰

KYRUKRFVOACELK-UHFFFAOYSA-N

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應用

Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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Appendix: Preparation of N-succinimidyl 3-(4-hydroxyphenyl)propionate.
J Rudinger et al.
The Biochemical journal, 133(3), 538-539 (1973-07-01)
D P McManus et al.
Journal of helminthology, 61(1), 47-52 (1987-03-01)
Living, intact protoscoleces of the British horse and sheep strains of Echinococcus granulosus were subjected to surface radioiodination procedures using 125I and Iodogen and 125I-Bolton Hunter reagent. Subsequent combined electron microscopy and autoradiography revealed specific surface membrane labelling with the
Radioiodination of cellular proteins.
Caplan S, Baniyash M.
Current Protocols in Cell Biology, 7, 7-7 (2001)
Jae Jun Park et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(1), 56-62 (2010-10-05)
In this study, the radioiodination and biodistribution of quantum dots (QDs) using Bolton-Hunter reagent were investigated. Radioiodination yield was 33.4 ± 2.0%. Fluorescent intensity of radioiodinated QDs decreased to 75.4% of the maximum prior to radioiodination. In biodistribution and ex
Labeling of peptides and proteins by radioiodination.
Bailey GS.
Methods Mol. Cell Biol., 32, 441-448 (1994)
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